Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.52 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 3/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10473062 | 0.82 | CTSS (0.46) | PPARAPPARGCTSSATMCTSK | |
| SCHEMBL4630907 | 0.81 | MEN1 (0.52) | PPARAPPARGCTSSMEN1TSHR | |
| SCHEMBL6387549 | 0.81 | PPARA (0.49) | PPARAPPARGCTSSCTSKCTSL | |
| SCHEMBL241565 | 0.77 | CTSK (0.61) | CTSSMEN1KMT2AATMCTSK | |
| SCHEMBL241564 | 0.77 | CTSK (0.61) | CTSSMEN1KMT2AATMCTSK | |
| SCHEMBL856196 | 0.77 | CTSK (0.61) | CTSSMEN1KMT2AATMCTSK | |
| SCHEMBL7330223 | 0.77 | PPARA (0.71) | PPARAPPARGCTSSMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7400990 | 0.76 | CTSK (0.60) | CTSSMEN1KMT2AATMCTSK | |
| Hydrochloric Acid SCHEMBL7400995 | 0.76 | CTSK (0.60) | CTSSMEN1KMT2AATMCTSK | |
| SCHEMBL7334052 | 0.76 | ALDH1A1 (0.51) | PPARACTSSTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096334-A1 | PYRROLOPYRROLONES ACTIVE AS KINASE INHIBITORS | PFIZER ITALIA SRL (IT) | 2007-08-30 | — | — | WO | disclosed |