SCHEMBL534112

SCHEMBL534112

CCO[Si](C)(Cc1ccccc1)OCC

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.42
TSHR P16473 3/20 0.36
NR1H2 P55055 1/20 0.35
NR1H3 Q13133 1/20 0.35
ELANE P08246 1/20 0.35
CALM1 P0DP23 1/20 0.35
PPID Q08752 1/20 0.34
SMN1; SMN2 Q16637 3/20 0.33
ALDH1A1 P00352 2/20 0.33
LTA4H P09960 2/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
CYP2D6 P10635 1/20 0.33
IDO1 P14902 1/20 0.33
AOC3 Q16853 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19809435 0.91 TP53 (0.35) TP53NR1H2NR1H3ELANESMN1; SMN2
SCHEMBL19809228 0.90 TP53 (0.38) TP53TSHRNR1H2NR1H3ELANE
SCHEMBL16062864 0.89 ESR1 (0.39)
SCHEMBL19809388 0.83 TP53 (0.39) TP53TSHRNR1H2NR1H3ELANE
SCHEMBL109170 0.83 TP53 (0.42) TP53TSHRNR1H2NR1H3CALM1
SCHEMBL15734456 0.81 NR1H2 (0.40) TP53NR1H2NR1H3PPIDALDH1A1
SCHEMBL12458733 0.81 ESR1 (0.34)
SCHEMBL12458719 0.81 ESR1 (0.34)
SCHEMBL27922596 0.80 LTA4H (0.43) TP53TSHRSMN1; SMN2ALDH1A1LTA4H
SCHEMBL2806315 0.80 TP53 (0.44) TP53TSHRCALM1ALDH1A1LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 371 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3986366-B1 COMPOSITION COMPRISING AT LEAST ONE ALKOXYSILANE, AT LEAST ONE NON-AMINO SILICONE AND WATER, THE ALKOXYSILANE/NON-AMINO SILICONE MASS RATIO RANGING FROM 95/5 TO 5/95 OREAL (FR) 2024-09-11 EP claimed
CN-114007576-B Anhydrous composition comprising at least one aminosilicone, at least one alkoxysilane and at least one colorant 莱雅公司 2023-12-01 CN claimed
US-20220331228-A1 ANHYDROUS COMPOSITION COMPRISING AT LEAST ONE AMINO SILICONE, AT LEAST ONE ALKOXYSILANE AND AT LEAST ONE COLORING AGENT L'OREAL (FR) 2022-10-20 US claimed
EP-3986366-A1 COMPOSITION COMPRISING AT LEAST ONE ALKOXYSILANE, AT LEAST ONE NON-AMINO SILICONE AND WATER, THE ALKOXYSILANE/NON-AMINO SILICONE MASS RATIO RANGING FROM 95/5 TO 5/95 L'OREAL (FR) 2022-04-27 EP claimed
EP-3986361-A1 ANHYDROUS COMPOSITION COMPRISING AT LEAST ONE AMINO SILICONE, AT LEAST ONE ALKOXYSILANE AND AT LEAST ONE COLORING AGENT L'OREAL (FR) 2022-04-27 EP claimed
CN-114007576-A Anhydrous composition comprising at least one aminosilicone, at least one alkoxysilane and at least one colorant 莱雅公司 2022-02-01 CN claimed
WO-2021214053-A1 PROCESS FOR DENSIFYING KERATIN FIBERS, BASED ON SILICONE, AN ALKOXYSILANE AND A COLORING AGENT L'OREAL (FR) 2021-10-28 WO claimed
WO-2020260097-A1 ANHYDROUS COMPOSITION COMPRISING AT LEAST ONE AMINO SILICONE, AT LEAST ONE ALKOXYSILANE AND AT LEAST ONE COLORING AGENT L'OREAL (FR) 2020-12-30 WO claimed
WO-2020260273-A1 COMPOSITION COMPRISING AT LEAST ONE ALKOXYSILANE, AT LEAST ONE NON-AMINO SILICONE AND WATER, THE ALKOXYSILANE/NON-AMINO SILICONE MASS RATIO RANGING FROM 95/5 TO 5/95 L'OREAL (FR) 2020-12-30 WO claimed
US-9181399-B2 Method for producing polysiloxane TOAGOSEI CO., LTD. (JP) 2015-11-10 US claimed
CN-104302272-A Cosmetic composition comprising at least one alkoxysilane OREAL 2015-01-21 CN claimed
US-20140314696-A1 COSMETIC COMPOSITION COMPRISING AT LEAST ONE ALKOXYSILANE L'OREAL (FR) 2014-10-23 US claimed
US-20140303392-A1 METHOD FOR PRODUCING POLYSILOXANE TOAGOSEI CO., LTD. (JP) 2014-10-09 US claimed
EP-2776004-A2 COSMETIC COMPOSITION COMPRISING AT LEAST ONE ALKOXYSILANE L'OREAL (FR) 2014-09-17 EP claimed
WO-2013068979-A2 COSMETIC COMPOSITION COMPRISING AT LEAST ONE ALKOXYSILANE L'OREAL (FR) 2013-05-16 WO claimed
US-20260118764-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM AND SILICON-CONTAINING RESIST UNDERLAYER FILM NISSAN CHEMICAL CORPORATION (JP) 2026-04-30 US disclosed
EP-4731164-A1 COMPOSITE MATERIAL OF BISMUTH OXYCARBONATE AND ORGANOSILICON COMPOUNDS FOR FILTERING ULTRAVIOLET RADIATION L'OREAL (FR) 2026-04-29 EP disclosed
US-20050287392-A1 Organic electroluminescent device, method for producing the same, and electronic apparatus SEIKO EPSON CORPORATION (JP) 2005-12-29 US disclosed
CN-1713787-A Organic electroluminescent device, method for producing the same, and electronic apparatus SEIKO EPSON CORP (JP) 2005-12-28 CN disclosed
US-5445871-A Laminate; cured film of an actinic-radiation curable primer; an inorganic material layer formed on cured film by physical deposition KANSAI PAINT CO., LTD. (JP) 1995-08-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260118764-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM AND SILICON-CONTAINING RESIST UNDERLAYER FILM SRSF1, MACF1, SRPK1 TP53 2101/4885TSHR 4084/4885NR1H2 804/4885
US-20220331228-A1 ANHYDROUS COMPOSITION COMPRISING AT LEAST ONE AMINO SILICONE, AT LEAST ONE ALKOXYSILANE AND AT LEAST ONE COLORING AGENT KRT18, SHH, VIM TP53 978/4885TSHR 4502/4885NR1H2 4111/4885
US-20140314696-A1 COSMETIC COMPOSITION COMPRISING AT LEAST ONE ALKOXYSILANE YWHAZ, SCO2, PRKCZ TP53 463/4885TSHR 3737/4885NR1H2 2671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.