Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | PAM | P19021 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | YWHAG | P61981 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL670636 | 0.82 | L3MBTL1 (0.45) | ALDH1A1MAPK1L3MBTL1PAMHTT | |
| SCHEMBL6335041 | 0.82 | YWHAG (0.44) | ALDH1A1MAPK1L3MBTL1PAMHTT | |
| SCHEMBL14337072 | 0.81 | YWHAG (0.46) | ALDH1A1MAPK1L3MBTL1PAMHTT | |
| SCHEMBL6235811 | 0.80 | MAPK1 (0.43) | ALDH1A1MAPK1L3MBTL1PAMHIF1A | |
| SCHEMBL2767776 | 0.78 | SLC7A5 (0.55) | ALDH1A1SLC7A5SMN1; SMN2 | |
| SCHEMBL40418 | 0.73 | AKR1B1 (0.58) | ALDH1A1HTTHIF1APOLBTDP1 | |
| SCHEMBL5341838 | 0.72 | AKR1B1 (0.47) | ALDH1A1HTTHIF1APOLBTDP1 | |
| SCHEMBL8986802 | 0.72 | ALDH1A1 (0.39) | ALDH1A1POLBSLC7A5 | |
| SCHEMBL10906219 | 0.70 | PTPN1 (0.49) | ALDH1A1MAPK1L3MBTL1PAMHIF1A | |
| Ethylene Glycol SCHEMBL6232155 | 0.69 | AKR1B1 (0.52) | ALDH1A1HTTHIF1APOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6927247-B2 | Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers | THE COLLEGE OF WILLIAM AND MARY (US) | 2005-08-09 | — | — | US | claimed |
| EP-1521803-A2 | ORGANIC THIOL METAL-FREE STABILIZERS AND PLASTICIZERS FOR HALOGEN-CONTAINING POLYMERS | The College of William and Mary (US) | 2005-04-13 | — | — | EP | claimed |
| WO-2003106550-A2 | ORGANIC THIOL METAL-FREE STABILIZERS AND PLASTICIZERS FOR HALOGEN-CONTAINING POLYMERS | THE COLLEGE OF WILLIAM AND MARY (US) | 2003-12-24 | — | — | WO | claimed |
| US-20030220429-A1 | Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers | COLLEGE OF WILLIAM AND MARY, THE | 2003-11-27 | — | — | US | claimed |
| US-7312266-B2 | Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers | THE COLLEGE OF WILLIAM AND MARY (US) | 2007-12-25 | — | — | US | disclosed |
| US-6927247-B2 | Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers | THE COLLEGE OF WILLIAM AND MARY (US) | 2005-08-09 | — | — | US | disclosed |
| EP-1521803-A2 | ORGANIC THIOL METAL-FREE STABILIZERS AND PLASTICIZERS FOR HALOGEN-CONTAINING POLYMERS | The College of William and Mary (US) | 2005-04-13 | — | — | EP | disclosed |
| US-20050049307-A1 | Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers | COLLEGE OF WILLIAM AND MARY, THE | 2005-03-03 | — | — | US | disclosed |
| WO-2003106550-A2 | ORGANIC THIOL METAL-FREE STABILIZERS AND PLASTICIZERS FOR HALOGEN-CONTAINING POLYMERS | THE COLLEGE OF WILLIAM AND MARY (US) | 2003-12-24 | — | — | WO | disclosed |
| US-20030220429-A1 | Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers | COLLEGE OF WILLIAM AND MARY, THE | 2003-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050049307-A1 | Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers | TST, LANCL1, TTPA | ALDH1A1 203/4885MAPK1 2739/4885L3MBTL1 85/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.