SCHEMBL6235811

SCHEMBL6235811

O=C(Cc1ccc(S)cc1)OCC(COC(=O)Cc1ccc(S)cc1)(COC(=O)Cc1ccc(S)cc1)COC(=O)Cc1ccc(S)cc1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.43
ALDH1A1 P00352 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
PAM P19021 1/20 0.42
HIF1A Q16665 1/20 0.39
MAPT P10636 1/20 0.39
POLB P06746 1/20 0.38
CYP4F2 P78329 1/20 0.37
CYP4A11 Q02928 1/20 0.37
YWHAG P61981 1/20 0.37
GAA P10253 1/20 0.36
MGLL Q99685 2/20 0.36
KLK7 P49862 1/20 0.36
CYP4Z1 Q86W10 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5341827 0.80 ALDH1A1 (0.42) MAPK1ALDH1A1L3MBTL1PAMHIF1A
SCHEMBL184705 0.79 CYP4Z1 (0.54) MAPK1ALDH1A1L3MBTL1PAMMAPT
SCHEMBL6343515 0.79 L3MBTL1 (0.50) MAPK1ALDH1A1L3MBTL1PAMPOLB
SCHEMBL21634259 0.78 CYP4F2 (0.42) MAPK1ALDH1A1L3MBTL1PAMPOLB
SCHEMBL11031784 0.77 ALDH1A1 (0.44) MAPK1ALDH1A1L3MBTL1MAPTGAA
SCHEMBL9293361 0.75 MCL1 (0.43) ALDH1A1L3MBTL1MAPTCYP4F2CYP4A11
SCHEMBL166999 0.75 CYP4F2 (0.63) ALDH1A1L3MBTL1MAPTCYP4F2CYP4A11
SCHEMBL21880654 0.74 MTNR1A (0.46) MAPTPOLBCYP4F2CYP4A11
SCHEMBL11985734 0.69 CYP3A4 (0.57) ALDH1A1L3MBTL1MAPTKLK7
SCHEMBL165930 0.69 CA2 (0.62) ALDH1A1HIF1AMAPTPOLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6927247-B2 Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers THE COLLEGE OF WILLIAM AND MARY (US) 2005-08-09 US claimed
EP-1521803-A2 ORGANIC THIOL METAL-FREE STABILIZERS AND PLASTICIZERS FOR HALOGEN-CONTAINING POLYMERS The College of William and Mary (US) 2005-04-13 EP claimed
WO-2003106550-A2 ORGANIC THIOL METAL-FREE STABILIZERS AND PLASTICIZERS FOR HALOGEN-CONTAINING POLYMERS THE COLLEGE OF WILLIAM AND MARY (US) 2003-12-24 WO claimed
US-20030220429-A1 Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers COLLEGE OF WILLIAM AND MARY, THE 2003-11-27 US claimed
US-6927247-B2 Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers THE COLLEGE OF WILLIAM AND MARY (US) 2005-08-09 US disclosed
EP-1521803-A2 ORGANIC THIOL METAL-FREE STABILIZERS AND PLASTICIZERS FOR HALOGEN-CONTAINING POLYMERS The College of William and Mary (US) 2005-04-13 EP disclosed
WO-2003106550-A2 ORGANIC THIOL METAL-FREE STABILIZERS AND PLASTICIZERS FOR HALOGEN-CONTAINING POLYMERS THE COLLEGE OF WILLIAM AND MARY (US) 2003-12-24 WO disclosed
US-20030220429-A1 Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers COLLEGE OF WILLIAM AND MARY, THE 2003-11-27 US disclosed