Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.56 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1119176 | 0.86 | CES2 (0.59) | NR1H4ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL5300752 | 0.86 | ALOX5 (0.61) | NR1H4ALDH1A1ALOX5L3MBTL1LMNA | |
| SCHEMBL9725829 | 0.86 | FFAR1 (0.65) | NR1H4ALDH1A1ALOX5L3MBTL1LMNA | |
| SCHEMBL1203178 | 0.85 | ALOX5 (0.67) | NR1H4ALDH1A1ALOX5L3MBTL1LMNA | |
| SCHEMBL70341 | 0.82 | ALDH1A1 (0.63) | NR1H4ALDH1A1L3MBTL1LMNAMAOB | |
| SCHEMBL1171712 | 0.82 | NR1H4 (0.60) | NR1H4ALDH1A1L3MBTL1LMNAMAOB | |
| SCHEMBL2166377 | 0.82 | ALOX5 (0.65) | ALOX5L3MBTL1LMNALTB4RLTB4R2 | |
| SCHEMBL13875448 | 0.81 | ALDH1A1 (0.65) | NR1H4ALDH1A1ALOX5L3MBTL1LMNA | |
| SCHEMBL12894591 | 0.81 | NR1H4 (0.58) | NR1H4ALDH1A1ALOX5L3MBTL1LMNA | |
| SCHEMBL12894590 | 0.81 | NR1H4 (0.58) | NR1H4ALDH1A1ALOX5L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223881-B2 | Process for the preparation of new antidiabetic agents | DR. REDDY'S LABORATORIES LIMITED (IN) | 2007-05-29 | — | — | US | disclosed |
| US-20030125553-A1 | Process for the preparation of new antidiabetic agents | DR. REDDY'S LABORATORIES LIMITED | 2003-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030125553-A1 | Process for the preparation of new antidiabetic agents | GLP1R, GPR119, SLC5A1 | NR1H4 340/4885ALDH1A1 293/4885ALOX5 3558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.