⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4576487 | 0.84 | CA12 (0.42) | — | |
| SCHEMBL3901324 | 0.79 | LMNA (0.38) | — | |
| SCHEMBL29411044 | 0.78 | ACHE (0.50) | — | |
| SCHEMBL24031 | 0.78 | ACHE (0.50) | — | |
| SCHEMBL667751 | 0.75 | — | — | |
| SCHEMBL9117953 | 0.74 | HSP90AA1 (0.30) | — | |
| SCHEMBL29705684 | 0.74 | MAOB (0.46) | — | |
| SCHEMBL3428405 | 0.74 | MAOB (0.46) | — | |
| SCHEMBL3138349 | 0.73 | TP53 (0.53) | — | |
| SCHEMBL635453 | 0.73 | RXRA (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39678-E1 | Meiosis regulating compounds | NOVO NORDISK A/S (DK) | 2007-06-05 | — | — | US | disclosed |
| US-20050101573-A1 | Meiosis regulating compounds | NOVO NORDISK A/S (DK) | 2005-05-12 | — | — | US | disclosed |
| US-6884796-B2 | Meiosis regulating compounds | NOVONORDISK A/S (DK) | 2005-04-26 | — | — | US | disclosed |
| EP-0983251-B1 | ANTI-INFLAMMATORY PIPERAZINYL-BENZYL-TETRAZOLE DERIVATIVES AND INTERMEDIATES THEREOF | PFIZER LTD (GB) | 2004-06-23 | — | — | EP | disclosed |
| EP-1077992-B1 | USE OF MEIOSIS REGULATING COMPOUNDS | NOVO NORDISK AS (DK) | 2003-12-10 | — | — | EP | disclosed |
| US-6514975-B1 | Tetrazoles as selective agonists for the delta opioid receptor | PFIZER INC | 2003-02-04 | — | — | US | disclosed |
| US-20020183283-A1 | Meiosis regulating compounds | FAARUP PETER (DK) | 2002-12-05 | — | — | US | disclosed |
| US-6476248-B1 | Hydroxythiol grignard reaction synthesis | HONEYWELL INTERNATIONAL, INC. | 2002-11-05 | — | — | US | disclosed |
| US-6407086-B2 | NOVEL STEROL DERIVATIVES USED FOR REGULATING THE MEIOSIS IN OOCYTES AND IN MALE GERM CELLS | NOVO NORDISK A/S (DK) | 2002-06-18 | — | — | US | disclosed |
| EP-1140812-A2 | HYDROXYTHIOL GRIGNARD REACTION SYNTHESIS | Alliedsignal, Inc. (US) | 2001-10-10 | — | — | EP | disclosed |
| US-20010003782-A1 | Meiosis regulating compounds | NOVA NORDISK A/S (DK) | 2001-06-14 | — | — | US | disclosed |
| US-6200978-B1 | FOR PREVENTING OR TREATING INFLAMMATORY DISEASES SUCH AS ARTHRITIS, PSORIASIS, ASTHMA, OR INFLAMMATORY BOWEL DISEASE, DISORDERS OF RESPIRATORY FUNCTION, GASTROINTESTINAL DISORDERS SUCH AS FUNCTIONAL BOWEL DISEASE, AS ANALGESICS | PFIZER INC. | 2001-03-13 | — | — | US | disclosed |
| EP-1077992-A1 | MEIOSIS REGULATING COMPOUNDS | NOVO NORDISK A/S (DK) | 2001-02-28 | — | — | EP | disclosed |
| WO-2000035866-A2 | HYDROXYTHIOL GRIGNARD REACTION SYNTHESIS | ALLIEDSIGNAL, INC. (US) | 2000-06-22 | — | — | WO | disclosed |
| US-6054623-A | Hydroxythiol grignard reaction synthesis | ALLIEDSIGNAL INC. (US) | 2000-04-25 | — | — | US | disclosed |
| EP-0983251-A1 | ANTI-INFLAMMATORY PIPERAZINYL-BENZYL-TETRAZOLE DERIVATIVES AND INTERMEDIATES THEREOF | Pfizer Limited (GB) | 2000-03-08 | — | — | EP | disclosed |
| WO-1999058549-A1 | MEIOSIS REGULATING COMPOUNDS | NOVO NORDISK A/S (DK) | 1999-11-18 | — | — | WO | disclosed |
| WO-1998052929-A1 | ANTI-INFLAMMATORY PIPERAZINYL-BENZYL-TETRAZOLE DERIVATIVES AND INTERMEDIATES THEREOF | PFIZER LIMITED (GB) | 1998-11-26 | — | — | WO | disclosed |