Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5873308 | 0.86 | CA2 (0.44) | KMT2ALMNAPOLBCA1CA2 | |
| SCHEMBL11794766 | 0.84 | F2 (0.49) | F2PRSS1PRSS2PRSS3KMT2A | |
| SCHEMBL973720 | 0.79 | CA1 (0.47) | F2PRSS1PRSS2PRSS3KMT2A | |
| SCHEMBL16897446 | 0.77 | PKM (0.50) | F2PRSS1PRSS2PRSS3KMT2A | |
| SCHEMBL9247417 | 0.76 | MAPT (0.48) | F2PRSS1PRSS2PRSS3KMT2A | |
| SCHEMBL3179301 | 0.76 | F2 (0.49) | F2PRSS1PRSS2PRSS3KMT2A | |
| SCHEMBL1551682 | 0.75 | F2 (0.50) | F2PRSS1PRSS2PRSS3KMT2A | |
| SCHEMBL8861762 | 0.74 | ALDH1A1 (0.50) | F2PRSS1PRSS2PRSS3KMT2A | |
| SCHEMBL3836056 | 0.74 | ALDH1A1 (0.58) | F2PRSS1PRSS2PRSS3KMT2A | |
| SCHEMBL29278756 | 0.74 | GAA (0.52) | F2PRSS1PRSS2PRSS3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109171092-B | Elastomer shoe and shoe making process thereof | 中国科学院化学研究所 | 2021-02-26 | — | — | CN | claimed |
| CN-109171092-A | A kind of elastic body shoe and its shoe-making process | 中国科学院化学研究所 | 2019-01-11 | — | — | CN | claimed |
| CN-109171092-B | Elastomer shoe and shoe making process thereof | 中国科学院化学研究所 | 2021-02-26 | — | — | CN | disclosed |
| CN-110819144-A | Low-temperature fast-curing solvent-free fireproof coating and preparation method thereof | 江苏朝晖化工有限公司 | 2020-02-21 | — | — | CN | disclosed |
| CN-109171092-A | A kind of elastic body shoe and its shoe-making process | 中国科学院化学研究所 | 2019-01-11 | — | — | CN | disclosed |
| US-7235671-B2 | Process for preparing 3-chloromethyl-1,2,4-triazolin-5-one | MERCK & CO. INC. (US) | 2007-06-26 | — | — | US | disclosed |
| US-20060052355-A1 | reacting a chloro contaiing triaryl- or trialkyl-orthoester with a sulfonic acid salt of semicarbazide in an organic solvent, adding a brine solution to the concentrated reaction mixture,cooling the mixture to form a solid product, acidification with aqueous acid | MERCK SHARP & DOHME CORP. | 2006-03-09 | — | — | US | disclosed |
| US-6991659-B2 | Production of tanned leather and products suitable therefore | CLARIANT FINANCE (BVI) LIMITED (VG) | 2006-01-31 | — | — | US | disclosed |
| EP-1549623-A4 | PROCESS FOR PREPARING 3-CHLOROMETHYL-1,2,4-TRIAZOLIN-5-ONE | MERCK & CO INC (US) | 2005-10-05 | — | — | EP | disclosed |
| EP-1549623-A2 | PROCESS FOR PREPARING 3-CHLOROMETHYL-1,2,4-TRIAZOLIN-5-ONE | Merck & Co., Inc. (US) | 2005-07-06 | — | — | EP | disclosed |
| US-20040074009-A1 | Production of tanned leather and products suitable therefore | CLARIANT FINANCE (BVI) LIMITED (VG) | 2004-04-22 | — | — | US | disclosed |
| WO-2004017898-A2 | PROCESS FOR PREPARING 3-CHLOROMETHYL-1,2,4-TRIAZOLIN-5-ONE | MERCK & CO., INC. (US) | 2004-03-04 | — | — | WO | disclosed |
| EP-1362128-A1 | PRODUCTION OF TANNED LEATHER AND PRODUCTS SUITABLE THEREFORE | Clariant Finance (BVI) Limited (VG) | 2003-11-19 | — | — | EP | disclosed |
| WO-2002059382-A1 | PRODUCTION OF TANNED LEATHER AND PRODUCTS SUITABLE THEREFORE | CLARIANT INTERNATIONAL LTD (CH) | 2002-08-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052355-A1 | reacting a chloro contaiing triaryl- or trialkyl-orthoester with a sulfonic acid salt of semicarbazide in an organic solvent, adding a brine solution to the concentrated reaction mixture,cooling the mixture to form a solid product, acidification with aqueous acid | CLIC1, CTRC, NISCH | F2 4061/4885PRSS1 200/4885PRSS2 453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.