SCHEMBL5353274

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9730987	0.79	MAOA (0.43)	ALDH1A1MAPTL3MBTL1CA12CA1
	SCHEMBL3807628	0.77	ALDH1A1 (0.49)	TP53ALDH1A1MAPTL3MBTL1MLYCD
	SCHEMBL6480081	0.77	ALDH1A1 (0.59)	TP53ALDH1A1MAPTL3MBTL1MLYCD
	SCHEMBL9731204	0.77	ALDH1A1 (0.44)	TP53ALDH1A1MAPTL3MBTL1S1PR1
	SCHEMBL642254	0.76	LMNA (0.52)	L3MBTL1LMNA
	Hydrochloric Acid SCHEMBL30527997	0.74	LMNA (0.50)	L3MBTL1LMNA
	SCHEMBL9730983	0.74	HCAR2 (0.41)	ALDH1A1MAPTL3MBTL1LMNA
	SCHEMBL9731029	0.73	SCN9A (0.41)	ALDH1A1MAPTL3MBTL1S1PR1MLYCD
	SCHEMBL9731409	0.73	NTRK2 (0.45)	ALDH1A1MAPTL3MBTL1
	SCHEMBL9731199	0.72	ALDH1A1 (0.40)	ALDH1A1MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.