Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 12/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9731204 | 0.94 | ALDH1A1 (0.44) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL6480080 | 0.85 | ALDH1A1 (0.53) | ALDH1A1MAPTL3MBTL1KMOKDM4E | |
| SCHEMBL9730983 | 0.81 | HCAR2 (0.41) | ALDH1A1MAPTL3MBTL1KDM4E | |
| SCHEMBL9731016 | 0.79 | HCAR2 (0.40) | ALDH1A1KMOKDM4E | |
| SCHEMBL6480081 | 0.78 | ALDH1A1 (0.59) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL9731397 | 0.78 | NTRK2 (0.41) | KMO | |
| SCHEMBL9731176 | 0.77 | HCAR2 (0.38) | KMO | |
| SCHEMBL9730987 | 0.73 | MAOA (0.43) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL5353274 | 0.72 | TP53 (0.42) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL71141 | 0.72 | KMO (0.59) | ALDH1A1MAPTKMOKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130317-A | Immunosuppressants and fibrosuppressants for metabolism of collagen | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-07-14 | — | — | US | disclosed |