SCHEMBL5354555

SCHEMBL5354555

O=S(O)c1ccccc1F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.41
CES1 P23141 3/20 0.41
G6PD P11413 1/20 0.41
ALDH1A1 P00352 2/20 0.38
ALOX15 P16050 1/20 0.38
NPC1 O15118 2/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HTR2A P28223 2/20 0.35
HTR2C P28335 2/20 0.35
KCNH2 Q12809 1/20 0.35
ACHE P22303 1/20 0.35
GAA P10253 1/20 0.34
NFE2L2 Q16236 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
BCHE P06276 1/20 0.33
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2932978 0.98 CES2 (0.39) CES2CES1G6PDALDH1A1ALOX15
SCHEMBL2932974 0.98 CES2 (0.39) CES2CES1G6PDALDH1A1ALOX15
SCHEMBL5042526 0.81 CES2 (0.45) CES2CES1G6PDALDH1A1ALOX15
SCHEMBL9153083 0.81 G6PD (0.50) CES2CES1G6PDALDH1A1ALOX15
SCHEMBL11859134 0.78 G6PD (0.48) CES2CES1G6PDALDH1A1ALOX15
SCHEMBL31236603 0.78 CES2 (0.37) CES2CES1G6PDALDH1A1ALOX15
SCHEMBL11423428 0.76 CES2 (0.35) CES2CES1G6PDALDH1A1NPC1
SCHEMBL9151925 0.74 G6PD (0.44) CES2CES1G6PDALDH1A1ALOX15
SCHEMBL29510897 0.73 HTR2A (0.35) CES2CES1G6PDALDH1A1ALOX15
SCHEMBL2932976 0.73 HTR2A (0.35) CES2CES1G6PDALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104628606-A Preparation method of sulfohydrazide compound WANG HUA 2015-05-20 CN claimed
CN-104513183-A Producing method of sodium 4-flurobenzenesulfinate TIANJIN RUIAN MEDICAL TECHNOLOGY DEV CO LTD 2015-04-15 CN claimed
US-5159082-A Catalytic coupling of an aromatic sulfinic acid with an aromatic halogen compound MITSUBISHI KASEI CORPORATION (JP) 1992-10-27 US claimed
EP-0405389-A1 Process for producing an aromatic compound Mitsubishi Chemical Corporation (JP) 1991-01-02 EP claimed
US-12221524-B2 Polymerization initiator, curable composition, dental material, and preparation kit for curable composition MITSUI CHEMICALS, INC. (JP) 2025-02-11 US disclosed
WO-2024190888-A1 DENTAL POLYMERIZATION KIT サンメディカル株式会社 2024-09-19 WO disclosed
WO-2024190887-A1 DENTAL POLYMERIZATION KIT サンメディカル株式会社 2024-09-19 WO disclosed
US-20240148613-A1 DENTAL POLYMERIZATION KIT SUN MEDICAL CO., LTD. (JP) 2024-05-09 US disclosed
EP-3835329-B1 POLYMERIZATION INITIATOR, CURABLE COMPOSITION, DENTAL MATERIAL, AND PREPARATION KIT FOR CURABLE COMPOSITION MITSUI CHEMICALS INC (JP) 2024-05-01 EP disclosed
WO-2024075641-A1 POLYMER MATERIAL FOR USE IN DENTISTRY サンメディカル株式会社 2024-04-11 WO disclosed
EP-4316453-A1 DENTAL POLYMERIZATION KIT Sun Medical Co., Ltd. (JP) 2024-02-07 EP disclosed
US-20230400766-A1 ONIUM SALT, RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-12-14 US disclosed
WO-2003094845-A2 PYRIDINE-BASED THYROID RECEPTOR LIGANDS BRISTOL-MYERS SQUIBB COMPANY (US) 2003-11-20 WO disclosed
US-20030073742-A1 Process for making bicalutamide and intermediates thereof SYNTHON B.V. (NL) 2003-04-17 US disclosed
EP-0405389-B1 Process for producing an aromatic compound MITSUBISHI CHEM IND (JP) 1995-01-04 EP disclosed
EP-0351332-B1 HERBICIDAL COMPOUNDS AND COMPOSITIONS CONTAINING THEM RHONE-POULENC AGROCHIMIE (FR) 1993-03-24 EP disclosed
US-5159082-A Catalytic coupling of an aromatic sulfinic acid with an aromatic halogen compound MITSUBISHI KASEI CORPORATION (JP) 1992-10-27 US disclosed
EP-0405389-A1 Process for producing an aromatic compound Mitsubishi Chemical Corporation (JP) 1991-01-02 EP disclosed
EP-0351332-A1 Herbicidal compounds and compositions containing them RHONE-POULENC AGROCHIMIE (FR) 1990-01-17 EP disclosed
US-4097669-A FUNGICIDES, BACTERICIDES, INSECTICIDES, ARTHROPODICIDES BAYER AKTIENGESELLSCHAFT (DT) 1978-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030073742-A1 Process for making bicalutamide and intermediates thereof BLVRB, BRDT, OTUB1 CES2 809/4885CES1 2076/4885G6PD 1547/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.