Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 6/20 | 0.37 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1801127 | 0.89 | CHRM2 (0.38) | CHRM2CHRM4CHRM1CHRM3SCN1A | |
| SCHEMBL17117556 | 0.79 | ACHE (0.44) | ACHE | |
| SCHEMBL1454465 | 0.77 | DNM1 (0.40) | ACHE | |
| SCHEMBL8084072 | 0.76 | EPHX2 (0.41) | EPHX2NPSR1ACHEALDH1A1 | |
| SCHEMBL30872097 | 0.76 | EPHX1 (0.45) | ACHE | |
| SCHEMBL27812694 | 0.75 | EPHX1 (0.44) | LMNAACHE | |
| SCHEMBL38663205 | 0.75 | NPC1 (0.42) | LMNASIRT2ACHESMN1; SMN2SIRT1 | |
| SCHEMBL38665201 | 0.75 | ACHE (0.45) | EPHX2ACHESMN1; SMN2 | |
| SCHEMBL5359786 | 0.74 | EPHX2 (0.35) | EPHX2MEN1KMT2ANPSR1LMNA | |
| SCHEMBL7626586 | 0.74 | EPHX2 (0.50) | EPHX2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113795435-A | Soluble package of pre-dosed powdered hair bleach | 莱雅公司 | 2021-12-14 | — | — | CN | disclosed |
| WO-2017108618-A1 | DYEING COMPOSITION COMPRISING AT LEAST 30% SURFACTANTS | L'OREAL (FR) | 2017-06-29 | — | — | WO | disclosed |
| WO-2017108619-A1 | OXIDIZING COMPOSITION COMPRISING AT LEAST 30% SURFACTANTS | L'OREAL (FR) | 2017-06-29 | — | — | WO | disclosed |
| WO-2017102650-A1 | DEVICE FOR DISPENSING A PRODUCT FOR DYEING AND/OR LIGHTENING KERATIN FIBRES COMPRISING AN ASSOCIATIVE POLYMER | L'OREAL (FR) | 2017-06-22 | — | — | WO | disclosed |
| WO-2017102651-A1 | DEVICE FOR DISPENSING A PRODUCT FOR DYEING AND/OR LIGHTENING KERATIN FIBRES COMPRISING A CATIONIC POLYMER | L'OREAL (FR) | 2017-06-22 | — | — | WO | disclosed |
| WO-2017102653-A1 | DEVICE FOR DISPENSING A PRODUCT FOR DYEING AND/OR LIGHTENING KERATIN FIBRES COMPRISING AT LEAST 7% OF SURFACTANTS | L'OREAL (FR) | 2017-06-22 | — | — | WO | disclosed |
| EP-2651516-B1 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 4-AMINOINDOLE COUPLER | L'ORÉAL (FR) | 2017-06-14 | — | — | EP | disclosed |
| US-9220671-B2 | Dye composition comprising at least four dye precursors including at least one oxidation base and at least one coupler | L'OREAL (FR) | 2015-12-29 | — | — | US | disclosed |
| US-9125834-B2 | Dye composition comprising a heterocyclic oxidation base and a 4-aminoindole coupler | L'OREAL (FR) | 2015-09-08 | — | — | US | disclosed |
| US-20140259454-A1 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 4-AMINOINDOLE COUPLER | L'OREAL (FR) | 2014-09-18 | — | — | US | disclosed |
| CN-103547249-A | Dye composition comprising at least four dye precursors including at least one oxidation base and at least one coupler | OREAL | 2014-01-29 | — | — | CN | disclosed |
| EP-2651516-A2 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 4-AMINOINDOLE COUPLER | L'Oréal (FR) | 2013-10-23 | — | — | EP | disclosed |
| EP-2651386-A2 | DYE COMPOSITION COMPRISING AT LEAST FOUR DYE PRECURSORS INCLUDING AT LEAST ONE OXIDATION BASE AND AT LEAST ONE COUPLER | L'Oréal (FR) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012080289-A2 | DYE COMPOSITION COMPRISING AT LEAST FOUR DYE PRECURSORS INCLUDING AT LEAST ONE OXIDATION BASE AND AT LEAST ONE COUPLER | L'OREAL (FR) | 2012-06-21 | — | — | WO | disclosed |
| WO-2012080287-A2 | DYE COMPOSITION COMPRISING A SECONDARY PARA-PHENYLENEDIAMINE OXIDATION BASE AND A CATIONIC 3,5-DIAMINOPYRIDINE COUPLER | L'OREAL (FR) | 2012-06-21 | — | — | WO | disclosed |
| WO-2012080285-A2 | DYE COMPOSITION COMPRISING A SECONDARY PARA-PHENYLENEDIAMINE OXIDATION BASE AND A 4-AMINOINDOLE COUPLER | L'OREAL (FR) | 2012-06-21 | — | — | WO | disclosed |
| WO-2012080321-A2 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 4-AMINOINDOLE COUPLER | L'OREAL (FR) | 2012-06-21 | — | — | WO | disclosed |
| US-7294152-B2 | Dyeing composition comprising at least one fluorindine compound for the dyeing of keratinic fibers, dyeing process comprising the composition and compound | L'OREAL S.A. (FR) | 2007-11-13 | — | — | US | disclosed |
| US-20050188475-A1 | Dyeing composition comprising at least one fluorindine compound for the dyeing of keratinic fibers, dyeing process comprising the composition and compound | L'OREAL S.A. (FR) | 2005-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140259454-A1 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 4-AMINOINDOLE COUPLER | KRT18, NDUFS5, NDUFS3 | CHRM2 3226/4885CHRM4 3102/4885CHRM1 3338/4885 |
| US-20050188475-A1 | Dyeing composition comprising at least one fluorindine compound for the dyeing of keratinic fibers, dyeing process comprising the composition and compound | KRT18, FLNA, FLNB | CHRM2 3037/4885CHRM4 2649/4885CHRM1 2703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.