SCHEMBL536267

SCHEMBL536267

CCOC(=O)[C@H](C)NC(=O)OCC#CI

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 11/20 0.38
METAP1 P53582 6/20 0.38
TYR P14679 1/20 0.33
LMNA P02545 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
TSHR P16473 1/20 0.31
CAD P27708 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9353137 0.87 TSHR (0.36) TYRSMN1; SMN2TSHRL3MBTL1
SCHEMBL536251 0.83 TYR (0.39) TYRSMN1; SMN2TSHR
SCHEMBL9845864 0.82 SMN1; SMN2 (0.39) SMN1; SMN2L3MBTL1
SCHEMBL11189746 0.80 METAP2 (0.46) METAP2METAP1TYRLMNAHTT
SCHEMBL22751568 0.80 METAP2 (0.46) METAP2METAP1TYRLMNAHTT
SCHEMBL9845863 0.79 SMN1; SMN2 (0.36) SMN1; SMN2L3MBTL1
SCHEMBL9845893 0.79 SMN1; SMN2 (0.36) SMN1; SMN2L3MBTL1
SCHEMBL9480087 0.78 CTSK (0.44) GAA
SCHEMBL9480524 0.75 CTSK (0.42) GAA
SCHEMBL9480506 0.75 CTSK (0.42) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240215572-A1 ANTIMICROBIAL PARTICLE DISPERSION MITSUBISHI PENCIL COMPANY, LIMITED (JP) 2024-07-04 US claimed
US-20170215421-A1 BIOCIDE AGENTS LANXESS DEUTSCHLAND GMBH (DE) 2017-08-03 US claimed
EP-2779830-B1 STABILIZATION OF COMPOUNDS CONTAINING IODINE HAVING POLYMERS COMPRISING NITROGEN LANXESS DEUTSCHLAND GMBH (DE) 2017-05-17 EP claimed
US-9585384-B2 Stabilization of compounds comprising iodine LANXESS DEUTSCHLAND GMBH (DE) 2017-03-07 US claimed
EP-3125688-A1 BIOCIDE AGENTS LANXESS Deutschland GmbH (DE) 2017-02-08 EP claimed
US-20160360753-A1 BIOCIDIC MICROCAPSULES LANXESS DEUTSCHLAND GMBH (DE) 2016-12-15 US claimed
US-9326502-B2 Stabilization of compounds containing iodine having polymers comprising nitrogen LANXESS DEUTSCHLAND GMBH (DE) 2016-05-03 US claimed
WO-2015150430-A1 BIOCIDE AGENTS LANXESS DEUTSCHLAND GMBH (DE) 2015-10-08 WO claimed
EP-2926659-A1 Biocidal agent LANXESS Deutschland GmbH (DE) 2015-10-07 EP claimed
US-20140303277-A1 STABILIZATION OF COMPOUNDS CONTAINING IODINE HAVING POLYMERS COMPRISING NITROGEN LANXESS DEUTSCHLAND GMBH (DE) 2014-10-09 US claimed
WO-2013072427-A1 STABILIZATION OF COMPOUNDS CONTAINING IODINE HAVING POLYMERS COMPRISING NITROGEN LANXESS DEUTSCHLAND GMBH (DE) 2013-05-23 WO claimed
EP-2594132-A1 Stabilisation of iodine containing compounds with polymers containing nitrogen Lanxess Deutschland GmbH (DE) 2013-05-22 EP claimed
WO-2012076699-A1 BIOCIDE MICROCAPSULE FORMULATIONS CONTAINING STABILISED IODINE-CONTAINING COMPOUNDS LANXESS DEUTSCHLAND GMBH (DE) 2012-06-14 WO claimed
EP-2462805-A1 Formulations containing stabilised compounds containing iodine LANXESS Deutschland GmbH (DE) 2012-06-13 EP claimed
EP-2440044-A2 INORGANIC CARRIER MATERIALS CONTAINING NITROGEN Lanxess Deutschland GmbH (DE) 2012-04-18 EP claimed
US-20110009268-A1 IPBC-CONTAINING COACERVATES LANXESS DEUTSCHLAND GMBH (DE) 2011-01-13 US claimed
EP-2270087-A1 Heterocyclic 3-ring connections and polymers containing iodine compounds LANXESS Deutschland GmbH (DE) 2011-01-05 EP claimed
WO-2010142795-A2 INORGANIC CARRIER MATERIALS CONTAINING NITROGEN LANXESS DEUTSCHLAND GMBH (DE) 2010-12-16 WO claimed
EP-1981629-A1 IPBC-CONTAINING COACERVATES Lanxess Deutschland GmbH (DE) 2008-10-22 EP claimed
WO-2007087994-A1 IPBC-CONTAINING COACERVATES LANXESS DEUTSCHLAND GMBH (DE) 2007-08-09 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140303277-A1 STABILIZATION OF COMPOUNDS CONTAINING IODINE HAVING POLYMERS COMPRISING NITROGEN NISCH, INMT, TPO METAP2 975/4885METAP1 1147/4885TYR 67/4885
US-20240215572-A1 ANTIMICROBIAL PARTICLE DISPERSION Q6ZSR9, PAM, ACMSD METAP2 4341/4885METAP1 3789/4885TYR 368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.