Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11714467 | 0.82 | HSP90AB1 (0.44) | P2RX7LMNAHTTL3MBTL1PKM | |
| SCHEMBL7890254 | 0.74 | CA12 (0.51) | LMNAHTTPKMALDH1A1KDM4E | |
| SCHEMBL1483489 | 0.74 | HTT (0.42) | P2RX7LMNAHTTPKMALDH1A1 | |
| SCHEMBL27503511 | 0.72 | SLC6A2 (0.31) | — | |
| SCHEMBL27521697 | 0.72 | ALDH1A1 (0.42) | LMNAHTTL3MBTL1PKMALDH1A1 | |
| SCHEMBL28701913 | 0.71 | TSHR (0.56) | LMNAL3MBTL1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL10275972 | 0.71 | MAPT (0.38) | P2RX7LMNAHTTL3MBTL1ALDH1A1 | |
| SCHEMBL1719924 | 0.70 | LMNA (0.47) | P2RX7LMNAHTTL3MBTL1ALDH1A1 | |
| SCHEMBL7769482 | 0.70 | P2RX7 (0.38) | P2RX7LMNAHTTL3MBTL1ALDH1A1 | |
| SCHEMBL5094342 | 0.69 | P2RX7 (0.41) | P2RX7LMNAHTTL3MBTL1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414351-A1 | NOVEL SALT OF 1,3,5-TRIAZINE-2,4,6-TRIAMINE DERIVATIVE | Astellas Pharma Inc. (JP) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010114162-A1 | NOVEL SALT OF 1,3,5-TRIAZINE-2,4,6-TRIAMINE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2010-10-07 | — | — | WO | disclosed |