Biphenyl

Biphenyl

SCHEMBL5370740

CCP(=O)(O)C(C)(C)C.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.47
TSHR P16473 2/20 0.47
MEN1 O00255 1/20 0.47
GAA P10253 1/20 0.47
PKM P14618 1/20 0.47
KMT2A Q03164 1/20 0.47
PTPN5 P54829 2/20 0.44
MAPT P10636 4/20 0.42
HPGD P15428 3/20 0.42
SMN1; SMN2 Q16637 3/20 0.41
ACP3 P15309 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
MAPK1 P28482 1/20 0.41
PTPN1 P18031 1/20 0.41
GGPS1 O95749 2/20 0.40
NPC1 O15118 1/20 0.39
LMNA P02545 1/20 0.39
CASP3 P42574 1/20 0.39
SENP8 Q96LD8 1/20 0.39
SENP7 Q9BQF6 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL27438624 0.81 ACP3 (0.54) ALDH1A1TSHRMEN1GAAPKM
SCHEMBL2406587 0.80
Biphenyl SCHEMBL10731115 0.74 HPGD (0.48) ALDH1A1PTPN5MAPTHPGDSMN1; SMN2
SCHEMBL10308636 0.73 HPGD (0.50) ALDH1A1TSHRMEN1GAAPKM
Biphenyl SCHEMBL377328 0.73 ACP3 (0.54) ALDH1A1PTPN5MAPTSMN1; SMN2ACP3
Biphenyl SCHEMBL342228 0.72 ALDH1A1 (0.60) ALDH1A1PTPN5ACP3PTPN1NPC1
Biphenyl SCHEMBL263925 0.72 ALDH1A1 (0.60) ALDH1A1PTPN5ACP3PTPN1NPC1
Biphenyl SCHEMBL3727875 0.72 ALDH1A1 (0.60) ALDH1A1PTPN5ACP3PTPN1NPC1
Biphenyl SCHEMBL3763955 0.72 ALDH1A1 (0.60) ALDH1A1PTPN5ACP3PTPN1NPC1
Biphenyl SCHEMBL1945860 0.72 ALDH1A1 (0.60) ALDH1A1PTPN5ACP3PTPN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007005172-A1 METHOD FOR THE PREPARATION OF ARALKYL DIALKYL PHOSPHONATES FERRO CORPORATION (US) 2007-01-11 WO claimed
US-20070004833-A1 METHOD FOR THE PREPARATION OF ARALKYL DIALKYL PHOSPHONATES FERRO CORPORATION (US) 2007-01-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070004833-A1 METHOD FOR THE PREPARATION OF ARALKYL DIALKYL PHOSPHONATES ADK, ARAF, RPN1 ALDH1A1 2327/4885TSHR 2324/4885MEN1 4182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.