Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6670685 | 0.86 | CYP3A4 (0.41) | GAAMAPTTHRBMEN1KMT2A | |
| SCHEMBL5368378 | 0.75 | MEN1 (0.34) | GAAMAPTTHRBMEN1KMT2A | |
| SCHEMBL5265250 | 0.73 | MAPT (0.47) | GAAMAPTTHRBMEN1KMT2A | |
| SCHEMBL6671389 | 0.71 | BACE1 (0.40) | GAAMAPTTHRBMEN1KMT2A | |
| SCHEMBL5375219 | 0.68 | MEN1 (0.31) | GAAMAPTTHRBMEN1KMT2A | |
| SCHEMBL24983667 | 0.66 | STING1 (0.42) | ALDH1A1SMN1; SMN2RAB9AHPGDMAOA | |
| SCHEMBL30141026 | 0.66 | STING1 (0.42) | ALDH1A1SMN1; SMN2RAB9AHPGDMAOA | |
| SCHEMBL24983417 | 0.66 | CYP3A4 (0.41) | ALDH1A1SMN1; SMN2RAB9AHPGDMAOA | |
| SCHEMBL24983815 | 0.66 | CYP3A4 (0.43) | ALDH1A1SMN1; SMN2RAB9AHPGDMAOA | |
| SCHEMBL30892456 | 0.66 | CYP3A4 (0.41) | ALDH1A1SMN1; SMN2RAB9AHPGDMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7268240-B2 | Synthetic methods for polyphenols | MARS, INC. | 2007-09-11 | — | — | US | disclosed |
| US-6849746-B2 | Synthetic methods for polyphenols | MARS, INC. (US) | 2005-02-01 | — | — | US | disclosed |
| US-20040235941-A1 | Dimer digallate compositions | MARS, INCORPORATED | 2004-11-25 | — | — | US | disclosed |
| US-20040236123-A1 | Synthetic methods for polyphenols | M&M/MARS INC. | 2004-11-25 | — | — | US | disclosed |
| US-20030176620-A1 | Synthetic methods for polyphenols | MARS INCORPORATED | 2003-09-18 | — | — | US | disclosed |
| US-6528664-B2 | Synthetic methods for polyphenols | MARS, INCORPORATED | 2003-03-04 | — | — | US | disclosed |
| EP-1027345-B1 | SYNTHETIC METHODS FOR POLYPHENOLS | MARS INC (US) | 2003-02-19 | — | — | EP | disclosed |
| US-20020128493-A1 | Coupling flavonoid-like compounds having protected hydroxy groups by functionalizing the C-4; oxidative dehydrogenation to form dimers and oligomers; efficiency; anticarciogenic agents; breast cancer | MARS, INCORPORATED | 2002-09-12 | — | — | US | disclosed |
| US-6420572-B1 | FLAVANOID DERIVATIVES AND PHENOLIC DERIVATIVES WITH HALOGENATION | MARS, INCORPORATED | 2002-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040236123-A1 | Synthetic methods for polyphenols | MLN, NQO1, NOD2 | GAA 2612/4885MAPT 1864/4885THRB 4387/4885 |
| US-20020128493-A1 | Coupling flavonoid-like compounds having protected hydroxy groups by functionalizing the C-4; oxidative dehydrogenation to form dimers and oligomers; efficiency; anticarciogenic agents; breast cancer | GPX4, NOX4, TPD52L2 | GAA 4447/4885MAPT 3573/4885THRB 3231/4885 |
| US-20040235941-A1 | Dimer digallate compositions | NOD2, GID4, GPX4 | GAA 3244/4885MAPT 1853/4885THRB 4397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.