Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | HPGD | P15428 | 4/20 | 0.62 |
| ▸ | F2 | P00734 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | C1R | P00736 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | HPN | P05981 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | UTRN | P46939 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5371556 | 0.87 | ALDH1A1 (0.60) | MAPTHSD17B10ALDH1A1HPGDF2 | |
| SCHEMBL10741223 | 0.83 | HPN (0.61) | MAPTHSD17B10ALDH1A1HPGDF2 | |
| SCHEMBL5385451 | 0.83 | HPN (0.52) | MAPTHSD17B10ALDH1A1HPGDF2 | |
| SCHEMBL5385483 | 0.82 | F7 (0.49) | MAPTHSD17B10ALDH1A1HPGDF2 | |
| SCHEMBL10344443 | 0.82 | ELANE (0.66) | MAPTALDH1A1HPGDF2KMT2A | |
| SCHEMBL5376370 | 0.82 | NPC1 (0.73) | MAPTHSD17B10ALDH1A1HPGDF2 | |
| SCHEMBL6563993 | 0.81 | MAPT (0.65) | MAPTHSD17B10ALDH1A1HPGDF2 | |
| SCHEMBL2537004 | 0.81 | MAPT (0.72) | MAPTHSD17B10ALDH1A1HPGDF2 | |
| SCHEMBL5227639 | 0.81 | UTRN (0.62) | MAPTHSD17B10ALDH1A1HPGDKMT2A | |
| SCHEMBL5382380 | 0.80 | ALDH1A1 (0.69) | MAPTHSD17B10ALDH1A1HPGDF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244776-B2 | Ultraviolet light absorbers | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-07-17 | — | — | US | disclosed |
| US-20070100031-A1 | Ultraviolet light absorbers | RAVICHANDRAN RAMANATHAN | 2007-05-03 | — | — | US | disclosed |
| US-7173128-B2 | Ultraviolet light absorbers | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-02-06 | — | — | US | disclosed |
| US-20040192684-A1 | Ultraviolet light absorbers | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-09-30 | — | — | US | disclosed |
| EP-1430038-A1 | ULTRAVIOLET LIGHT ABSORBERS | Ciba SC Holding AG (CH) | 2004-06-23 | — | — | EP | disclosed |
| WO-2003016292-A1 | ULTRAVIOLET LIGHT ABSORBERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-02-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192684-A1 | Ultraviolet light absorbers | UNG, MSH6, MAL2 | MAPT 904/4885HSD17B10 1172/4885ALDH1A1 131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.