SCHEMBL5385483

SCHEMBL5385483

CC(C)(c1ccccc1)c1ccc2nc(-c3cccc(C(F)(F)F)c3)oc(=O)c2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F7 P08709 1/20 0.49
F3 P13726 1/20 0.49
HPN P05981 1/20 0.48
KMT2A Q03164 8/20 0.47
ALDH1A1 P00352 5/20 0.47
HPGD P15428 3/20 0.47
F2 P00734 1/20 0.47
MEN1 O00255 7/20 0.47
NPC1 O15118 2/20 0.47
CYP1A2 P05177 2/20 0.47
CYP3A4 P08684 2/20 0.47
CYP2C19 P33261 2/20 0.47
CYP2C9 P11712 1/20 0.47
RAB9A P51151 1/20 0.47
MAPT P10636 3/20 0.47
HSD17B10 Q99714 1/20 0.47
ELANE P08246 2/20 0.46
NOTUM Q6P988 1/20 0.45
TP53 P04637 3/20 0.45
SMN1; SMN2 Q16637 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14462682 0.92 F7 (0.45) F7F3HPNKMT2AALDH1A1
SCHEMBL5380224 0.91 NPC1 (0.49) F7F3HPNKMT2AALDH1A1
SCHEMBL5382664 0.89 ELANE (0.57) HPNKMT2AALDH1A1HPGDF2
SCHEMBL5376751 0.87 KDM4E (0.51) HPNKMT2AALDH1A1HPGDF2
SCHEMBL14462683 0.87 NPC1 (0.55) KMT2AALDH1A1HPGDF2MEN1
SCHEMBL3452610 0.87 ELANE (0.60) F7F3HPNKMT2AALDH1A1
SCHEMBL5385451 0.86 HPN (0.52) F7F3HPNKMT2AALDH1A1
SCHEMBL5382380 0.84 ALDH1A1 (0.69) HPNKMT2AALDH1A1HPGDF2
SCHEMBL10344443 0.84 ELANE (0.66) F7F3KMT2AALDH1A1HPGD
SCHEMBL10741223 0.83 HPN (0.61) F7F3HPNKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7244776-B2 Ultraviolet light absorbers CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-07-17 US disclosed
US-20070100031-A1 Ultraviolet light absorbers RAVICHANDRAN RAMANATHAN 2007-05-03 US disclosed
US-7173128-B2 Ultraviolet light absorbers CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-02-06 US disclosed
US-20040192684-A1 Ultraviolet light absorbers CIBA SPECIALTY CHEMICALS CORPORATION 2004-09-30 US disclosed
EP-1430038-A1 ULTRAVIOLET LIGHT ABSORBERS Ciba SC Holding AG (CH) 2004-06-23 EP disclosed
WO-2003016292-A1 ULTRAVIOLET LIGHT ABSORBERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-02-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040192684-A1 Ultraviolet light absorbers UNG, MSH6, MAL2 F7 1356/4885F3 3151/4885HPN 1301/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.