Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL475141 | 0.83 | ALDH1A1 (0.46) | KRASKMT2AALDH1A1KDM4EMAPK1 | |
| SCHEMBL10336282 | 0.76 | ALDH1A1 (0.40) | KRASKMT2AALDH1A1KDM4EMAPK1 | |
| SCHEMBL256845 | 0.74 | ACHE (0.50) | KRASKMT2AALDH1A1KDM4EMAPK1 | |
| SCHEMBL29669870 | 0.74 | NFE2L2 (0.50) | KRASKMT2AALDH1A1KDM4EMAPK1 | |
| SCHEMBL1627720 | 0.74 | NFE2L2 (0.50) | KRASKMT2AALDH1A1KDM4EMAPK1 | |
| SCHEMBL1567125 | 0.74 | SMN1; SMN2 (0.50) | KMT2AALDH1A1KDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL5647650 | 0.73 | KMT2A (0.38) | KRASKMT2AALDH1A1KDM4EMAPK1 | |
| SCHEMBL3103447 | 0.73 | KMT2A (0.41) | KRASKMT2AALDH1A1KDM4EMAPK1 | |
| SCHEMBL1703057 | 0.73 | TAS1R3 (0.45) | KMT2AALDH1A1KDM4ESMN1; SMN2SLC6A2 | |
| SCHEMBL6885179 | 0.73 | KMT2A (0.38) | KRASKMT2AALDH1A1KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7282246-B2 | Fluorinated xanthenes and use thereof in liquid-crystal mixtures | MERCK PATENT GMBH (DE) | 2007-10-16 | — | — | US | disclosed |
| US-20050274929-A1 | Fluorinated xanthenes and use thereof in liquid-crystal mixtures | MERCK PATENT GMBH (DE) | 2005-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050274929-A1 | Fluorinated xanthenes and use thereof in liquid-crystal mixtures | CHRM1, HAX1, CHRM2 | KRAS 1169/4885KMT2A 3319/4885ALDH1A1 3316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.