Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5377943 | 0.85 | TSHR (0.33) | TSHRDAONAPRTMAPTATM | |
| SCHEMBL28206375 | 0.76 | PAX8 (0.35) | TSHRDAONAPRTMAPTATM | |
| SCHEMBL23045171 | 0.72 | ATM (0.40) | TSHRDAONAPRTMAPTATM | |
| SCHEMBL8733750 | 0.69 | TSHR (0.33) | TSHRDAONAPRTMAPTATM | |
| SCHEMBL5494133 | 0.69 | PAX8 (0.33) | — | |
| SCHEMBL11654664 | 0.69 | MAOA (0.39) | TSHRDAONAPRTMAPTATM | |
| SCHEMBL1408930 | 0.67 | TSHR (0.41) | TSHRDAONAPRTMAPTATM | |
| SCHEMBL3955962 | 0.66 | MAPT (0.33) | MAPTCES2CES1 | |
| SCHEMBL27788524 | 0.65 | TSHR (0.46) | TSHRDAONAPRTMAPTATM | |
| SCHEMBL4795729 | 0.64 | ESR1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007302721-A | SILOXANE DERIVATIVE AND SILOXANE DERIVATIVE-COATING INORGANIC OXIDE | TOKYO INSTITUTE OF TECHNOLOGY | 2007-11-22 | — | — | JP | disclosed |