Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.41 |
| ▸ | NPC1 | O15118 | 10/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18631865 | 0.86 | RAB9A (0.41) | RAB9ANPC1POLBCASP3SENP7 | |
| SCHEMBL537590 | 0.82 | MAPT (0.39) | RAB9ANPC1POLBCASP3SENP7 | |
| SCHEMBL17609266 | 0.77 | NPC1 (0.65) | RAB9ANPC1POLBCASP3SENP7 | |
| SCHEMBL17609264 | 0.70 | MAPT (0.40) | RAB9ANPC1POLBCASP3SENP7 | |
| SCHEMBL6116948 | 0.70 | RAB9A (0.40) | RAB9ANPC1POLBCASP3SENP7 | |
| SCHEMBL14365376 | 0.68 | MEN1 (0.44) | RAB9AKDM4EALDH1A1LMNAGAA | |
| SCHEMBL18554501 | 0.65 | RAB9A (0.45) | RAB9ANPC1POLBCASP3SENP7 | |
| SCHEMBL18554502 | 0.65 | RAB9A (0.45) | RAB9ANPC1POLBCASP3SENP7 | |
| SCHEMBL282088 | 0.64 | CYP3A4 (0.52) | RAB9ANPC1KDM4EALDH1A1MAPT | |
| SCHEMBL2900206 | 0.64 | DDAH1 (0.55) | ALDH1A1LMNASMN1; SMN2GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3091014-A1 | FLUORESCENT CELLULAR MARKERS | Zayas, Beatriz (US) | 2016-11-09 | — | — | EP | disclosed |
| US-8124770-B2 | Fluorescent cellular markers | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-02-28 | — | — | US | disclosed |
| EP-2414355-A2 | FLUORESCENT CELLULAR MARKERS | Zayas, Beatriz (US) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010135751-A2 | FLUORESCENT CELLULAR MARKERS | BEATRIZ ZAYAS BEATRIZ (US) | 2010-11-25 | — | — | WO | disclosed |
| US-20100256378-A1 | FLUORESCENT CELLULAR MARKERS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256378-A1 | FLUORESCENT CELLULAR MARKERS | AIFM1, CASP3, BAX | RAB9A 862/4885NPC1 1894/4885POLB 1321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.