SCHEMBL17609266

SCHEMBL17609266

Nc1ccc(Cl)c(C=Cc2nc3ccccc3[nH]2)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 12/20 0.65
▸ RAB9A P51151 12/20 0.65
▸ ALDH1A1 P00352 12/20 0.65
▸ MAPT P10636 11/20 0.65
▸ SMN1; SMN2 Q16637 10/20 0.65
▸ HPGD P15428 9/20 0.65
▸ KDM4E B2RXH2 8/20 0.65
▸ MEN1 O00255 8/20 0.65
▸ KMT2A Q03164 8/20 0.65
▸ HTT P42858 6/20 0.65
▸ LMNA P02545 5/20 0.65
▸ GAA P10253 5/20 0.65
▸ PKM P14618 3/20 0.65
▸ GLA P06280 3/20 0.65
▸ ALPL P05186 1/20 0.65
▸ ALPG P10696 1/20 0.65
▸ NFKB1 P19838 2/20 0.58
▸ NFKB2 Q00653 2/20 0.58
▸ RELA Q04206 2/20 0.58
▸ RECQL P46063 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL704507 0.80 RAB9A (0.62) NPC1RAB9AALDH1A1MAPTSMN1; SMN2
SCHEMBL704508 0.80 RAB9A (0.62) NPC1RAB9AALDH1A1MAPTSMN1; SMN2
SCHEMBL7808579 0.79 NPC1 (1.00) NPC1RAB9AALDH1A1MAPTSMN1; SMN2
SCHEMBL1086985 0.77 ALDH1A1 (0.81) NPC1RAB9AALDH1A1MAPTSMN1; SMN2
SCHEMBL29539476 0.77 ALDH1A1 (0.81) NPC1RAB9AALDH1A1MAPTSMN1; SMN2
SCHEMBL1086983 0.77 ALDH1A1 (0.81) NPC1RAB9AALDH1A1MAPTSMN1; SMN2
SCHEMBL537590 0.77 MAPT (0.39) NPC1RAB9AALDH1A1MAPTSMN1; SMN2
SCHEMBL537589 0.77 RAB9A (0.41) NPC1RAB9AALDH1A1MAPTSMN1; SMN2
SCHEMBL6481418 0.77 NPC1 (0.76) NPC1RAB9AALDH1A1MAPTSMN1; SMN2
SCHEMBL6479916 0.77 RAB9A (0.61) NPC1RAB9AALDH1A1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240066023-A1 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition SISTEMA UNIVERSITARIO ANA G. MENDEZ, INC. (US) 2024-02-29 — — US disclosed
US-11786520-B2 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition SISTEMA UNIV ANA G MENDEZ INC (US) 2023-10-17 — — US disclosed
US-11311531-B2 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition SISTEMA UNIV ANA G MENDEZ INC (US) 2022-04-26 — — US disclosed
US-20210290615-A1 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition SISTEMA UNIVERSITARIO ANA G. MENDEZ, INC. (US) 2021-09-23 — — US disclosed
US-20200261441-A1 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition SISTEMA UNIVERSITARIO ANA G. MENDEZ, INC. (US) 2020-08-20 — — US disclosed
US-20200246328-A1 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition SISTEMA UNIVERSITARIO ANA G. MENDEZ, INC. (US) 2020-08-06 — — US disclosed
US-10624885-B2 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition SISTEMA UNIV ANA G MENDEZ INC (US) 2020-04-21 — — US disclosed
US-20180214441-A1 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition SISTEMA UNIVERSITARIO ANA G. MENDEZ, INC. (US) 2018-08-02 — — US disclosed
US-9889128-B2 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition Sistema Universitario Ana G. Mendez (PR) 2018-02-13 — — US disclosed
US-20180008590-A9 METHOD FOR PRODUCING BENZAZOLOQUINOLIUM (BQS) SALTS AND USING THE BIOLOGICAL ACTIVITY OF THE COMPOSITION SISTEMA UNIVERSITARIO ANA G. MENDEZ, INC. (US) 2018-01-11 — — US disclosed
US-20170079973-A1 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition SISTEMA UNIVERSITARIO ANA G. MENDEZ, INC. (US) 2017-03-23 — — US disclosed
WO-2016044636-A2 METHOD FOR PRODUCING BENZAZOLOQUINOLIUM (BQS) SALTS AND USING THE BIOLOGICAL ACTIVITY OF THE COMPOSITION SISTEMA UNIVERSITARIO ANA G. MENDEZ, INC. (US) 2016-03-24 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11786520-B2 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition AHNAK, RECQL, NBAS NPC1 1719/4885RAB9A 2184/4885ALDH1A1 2342/4885
US-11311531-B2 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition RECQL, AHNAK, NDUFS1 NPC1 1601/4885RAB9A 2036/4885ALDH1A1 2214/4885
US-20200246328-A1 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition RECQL, AHNAK, NDUFS1 NPC1 1601/4885RAB9A 2036/4885ALDH1A1 2214/4885
US-10624885-B2 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition RECQL, AHNAK, NDUFS1 NPC1 1601/4885RAB9A 2036/4885ALDH1A1 2214/4885
US-20180008590-A9 METHOD FOR PRODUCING BENZAZOLOQUINOLIUM (BQS) SALTS AND USING THE BIOLOGICAL ACTIVITY OF THE COMPOSITION RECQL, AHNAK, NDUFS1 NPC1 1601/4885RAB9A 2036/4885ALDH1A1 2214/4885
US-20210290615-A1 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition AHNAK, RECQL, NBAS NPC1 1719/4885RAB9A 2184/4885ALDH1A1 2342/4885
US-20180214441-A1 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition RECQL, AHNAK, NDUFS1 NPC1 1601/4885RAB9A 2036/4885ALDH1A1 2214/4885
US-20240066023-A1 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition AHNAK, RECQL, NBAS NPC1 1719/4885RAB9A 2184/4885ALDH1A1 2342/4885
US-20200261441-A1 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition RECQL, AHNAK, NDUFS1 NPC1 1601/4885RAB9A 2036/4885ALDH1A1 2214/4885
US-20170079973-A1 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition RECQL, AHNAK, NDUFS1 NPC1 1601/4885RAB9A 2036/4885ALDH1A1 2214/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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