Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.95 |
| ▸ | ARG2 | P78540 | 4/20 | 0.57 |
| ▸ | ARG1 | P05089 | 3/20 | 0.57 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.56 |
| ▸ | NOS2 | P35228 | 5/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | NOS1 | P29475 | 3/20 | 0.50 |
| ▸ | NOS3 | P29474 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | GRM8 | O00222 | 1/20 | 0.50 |
| ▸ | GRM6 | O15303 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.50 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.50 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL12077750 | 1.00 | GSR (0.95) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL12077749 | 1.00 | GSR (0.95) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL12077745 | 1.00 | GSR (0.95) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL7343 | 0.98 | GSR (1.00) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL3359527 | 0.98 | GSR (1.00) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL456381 | 0.98 | GSR (1.00) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL1000151 | 0.98 | GSR (1.00) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL2802757 | 0.98 | GSR (1.00) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL668975 | 0.98 | GSR (1.00) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL15303774 | 0.98 | GSR (1.00) | GSRARG2ARG1RNPEPNOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116078408-B | Modified heterojunction Fenton photocatalyst, preparation method, application, special system and treatment method | 东南大学 | 2024-09-06 | — | — | CN | claimed |
| CN-116078408-A | Modified heterojunction Fenton photocatalyst, preparation method, application, special system and treatment method | 东南大学 | 2023-05-09 | — | — | CN | claimed |
| CN-116078408-B | Modified heterojunction Fenton photocatalyst, preparation method, application, special system and treatment method | 东南大学 | 2024-09-06 | — | — | CN | disclosed |
| CN-116078408-A | Modified heterojunction Fenton photocatalyst, preparation method, application, special system and treatment method | 东南大学 | 2023-05-09 | — | — | CN | disclosed |
| US-7195772-B2 | Amino-acid iodine complex | ZENG XIONGFEI | 2007-03-27 | — | — | US | disclosed |
| US-20030171598-A1 | Aminoacid-iodine complex | ZENG XIONGFEI (CN) | 2003-09-11 | — | — | US | disclosed |
| US-5230883-A | Method for localization and treatment of tumors using polylysine complexes | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1993-07-27 | — | — | US | disclosed |
| EP-0471790-A4 | METHOD FOR LOCALIZATION AND TREATMENT OF TUMORS AND COMPLEXES THEREFOR | — | 1992-07-08 | — | — | EP | disclosed |
| EP-0471790-A1 | METHOD FOR LOCALIZATION AND TREATMENT OF TUMORS AND COMPLEXES THEREFOR | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1992-02-26 | — | — | EP | disclosed |
| WO-1990013256-A1 | METHOD FOR LOCALIZATION AND TREATMENT OF TUMORS AND COMPLEXES THEREFOR | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1990-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171598-A1 | Aminoacid-iodine complex | BCAT1, BCAT2, DAO | GSR 1637/4885ARG2 1987/4885ARG1 1307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.