SCHEMBL538388

SCHEMBL538388

O=C(CS)OCC(CO)(CO)CO

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.43
TP53 P04637 1/20 0.43
CYP3A4 P08684 1/20 0.43
MAPK1 P28482 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HIF1A Q16665 1/20 0.43
TSHR P16473 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL331392 0.95 ALDH1A1 (0.48) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL538076 0.95 ALDH1A1 (0.43) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL31483866 0.92 ALDH1A1 (0.42) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL11586781 0.89 ALDH1A1 (0.39) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL6679883 0.89 ALDH1A1 (0.44) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL60561 0.87 TSHR (0.43) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL4820921 0.87 ALDH1A1 (0.38) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL538874 0.87 ALDH1A1 (0.38) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL31483844 0.87 ALDH1A1 (0.42) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL13265138 0.86 ALDH1A1 (0.41) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119431247-A Cation-pi action-containing degradable tough epoxy resin and preparation method thereof 哈尔滨工业大学 2025-02-14 CN claimed
CN-117645771-A Solvent-free high-low temperature resistant bulletproof composite matrix resin and preparation method thereof 上海鑫丰泰新材料科技有限公司 2024-03-05 CN claimed
CN-111019093-B Room-temperature rapid epoxy curing agent and application thereof in preparation of epoxy dry-hanging adhesive 武汉市科达云石护理材料有限公司 2022-05-03 CN claimed
CN-111592478-B Method for reducing chroma of pentaerythritol ester 山东益丰生化环保股份有限公司 2021-07-27 CN claimed
CN-111334350-A High-cleanness composite biodiesel and preparation method thereof 宜宾中通环保科技有限公司 2020-06-26 CN claimed
CN-111019093-A Room-temperature rapid epoxy curing agent and application thereof in preparation of epoxy dry-hanging adhesive 武汉市科达云石护理材料有限公司 2020-04-17 CN claimed
US-12503427-B2 Diamine composition, and method of preparing diisocyanate composition SK pucore co., ltd (KR) 2025-12-23 US disclosed
US-20250188329-A1 CURABLE COMPOSITION PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2025-06-12 US disclosed
CN-119371908-B Bending-resistant acrylic ester adhesive film and preparation method and application thereof 博益鑫成高分子材料股份有限公司 2025-05-02 CN disclosed
CN-119431247-A Cation-pi action-containing degradable tough epoxy resin and preparation method thereof 哈尔滨工业大学 2025-02-14 CN disclosed
CN-119371908-A Bending-resistant acrylic ester adhesive film and preparation method and application thereof 博益鑫成高分子材料股份有限公司 2025-01-28 CN disclosed
CN-119144246-A Polyethylene terephthalate protective film and preparation method thereof 珠海市一心材料科技有限公司 2024-12-17 CN disclosed
US-12146023-B2 Method for manufacturing diisocyanate and optical lens WOORI FINE CHEM CO., LTD. (KR) 2024-11-19 US disclosed
JP-2001031645-A PURIFIED PENTAERYTHRITOL POLY(THIOGLYCOLATE) AND PURIFICATION THEREOF MITSUI CHEMICALS INC 2001-02-06 JP disclosed
US-5942158-A PHOTOCHROMIC ARTICLE PPG INDUSTRIES OHIO, INC. (US) 1999-08-24 US disclosed
US-5932681-A PHOTOCHROMIC ARTICLE PPG INDUSTRIES OHIO, INC. (US) 1999-08-03 US disclosed
EP-0909755-A1 Thio-/mercapto-derivatives and use as antioxidant additives EXXON RESEARCH AND ENGINEERING COMPANY (US) 1999-04-21 EP disclosed
US-4851460-A Aqueous coating composition, process for its preparation and its use HERBERTS GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-07-25 US disclosed
US-4581401-A COPOLYMER OF METAL METHACRYLATE, ALLYL METHACRYLATE AND AN ORGANOSULFUR COMPOUND ROHM GMBH (DE) 1986-04-08 US disclosed
EP-0123223-A2 Laser recording medium FUJI PHOTO FILM CO., LTD. (JP) 1984-10-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12146023-B2 Method for manufacturing diisocyanate and optical lens SMO, CRYAA, INCENP ALDH1A1 3131/4885TP53 2298/4885CYP3A4 2523/4885
US-12503427-B2 Diamine composition, and method of preparing diisocyanate composition INCENP, ALKBH5, TET1 ALDH1A1 2551/4885TP53 4433/4885CYP3A4 3512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.