SCHEMBL538874

SCHEMBL538874

CCC(CO)(COC(=O)CS)COC(=O)CS

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HIF1A Q16665 1/20 0.38
TSHR P16473 1/20 0.38
HSD17B10 Q99714 1/20 0.38
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4820921 0.96 ALDH1A1 (0.38) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL16314428 0.93 ALDH1A1 (0.34) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL18289509 0.93 THRB (0.39) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL60815 0.90 TSHR (0.42) ALDH1A1MAPK1HIF1ATSHRHSD17B10
SCHEMBL11585849 0.90 TSHR (0.42) ALDH1A1TSHRHSD17B10THRB
SCHEMBL331392 0.87 ALDH1A1 (0.48) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL538076 0.87 ALDH1A1 (0.43) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL538388 0.87 ALDH1A1 (0.43) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL538021 0.85 ALDH1A1 (0.36) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL18334182 0.84 THRB (0.43) TSHRHSD17B10THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 274 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3581600-B1 RESIN LENS AND PREPARATION METHOD THEREFOR EFIRM NEW MAT CO LTD (CN) 2025-01-08 EP claimed
US-11548971-B2 Method for producing a resin lens from a polyisocyanate and release agent at reduced pressure YIFENG NEW MATERIALS CO., LTD. (CN) 2023-01-10 US claimed
US-20210221940-A1 RESIN LENS AND METHOD FOR PRODUCING THE SAME SHANDONG EFIRM BIOCHEMISTRY AND ENVIRONMENTAL PROTECTION CO., LTD. (CN) 2021-07-22 US claimed
US-4162354-A MERCAPTANS AND HALOGENATED HYDROCARBONS THE FIRESTONE TIRE & RUBBER CO. (US) 1979-07-24 US claimed
US-12534563-B2 Block copolymer, resin composition, stretch conductor, electronic device, and pressure-sensitive adhesive film ARTIENCE CO., LTD. (JP) 2026-01-27 US disclosed
EP-4620947-A1 ISOCYANATE COMPOSITION, MODIFIED ISOCYANATE, POLYURETHANE RESIN AND OPTICAL MATERIAL Wanhua Chemical Group Co., Ltd. (CN) 2025-09-24 EP disclosed
US-12359016-B2 Method of preparing low haze polymer compositions for use in high refractive index optical materials PPG INDUSTRIES OHIO, INC. (US) 2025-07-15 US disclosed
US-20250197555-A1 ISOCYANATE COMPOSITION, MODIFIED ISOCYANATE, POLYURETHANE RESIN AND OPTICAL MATERIAL WANHUA CHEMICAL GROUP CO., LTD. (CN) 2025-06-19 US disclosed
US-12297301-B2 High-molecular-weight compound and method for producing same, composition and method for producing same, resin composition, additive for lubricating oil, and lubricating oil MITSUBISHI CHEMICAL CORPORATION (JP) 2025-05-13 US disclosed
EP-3581600-B1 RESIN LENS AND PREPARATION METHOD THEREFOR EFIRM NEW MAT CO LTD (CN) 2025-01-08 EP disclosed
EP-3325532-B1 COMPOSITION FOR PREPARING MOLDED POLYMERIC ARTICLE PPG IND OHIO INC (US) 2024-09-04 EP disclosed
WO-2024103321-A1 ISOCYANATE COMPOSITION, MODIFIED ISOCYANATE, POLYURETHANE RESIN AND OPTICAL MATERIAL 万华化学集团股份有限公司 2024-05-23 WO disclosed
US-5059673-A bis(isocyanatomethyl)-norbornane or -4,7methonohexahydroindan e high refractive index, lightweight, high impact MITSUI TOATSU CHEMICALS, INC. (JP) 1991-10-22 US disclosed
US-5047576-A Polymerizable vinyl compound having polythioether skeleton SHOWA DENKO KABUSHIKI KAISHA (JP) 1991-09-10 US disclosed
EP-0422836-A2 Resin for urethane lenses, lenses comprising the resin, and a process for preparation of the resin and the lenses MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-04-17 EP disclosed
EP-0374258-A1 HIGH REFRACTIVE INDEX LENS AND METHOD FOR ITS PRODUCTION MITSUI CHEMICALS, INC. (JP) 1990-06-27 EP disclosed
EP-0284374-A2 Polymerizable vinyl compound having polythioether skeleton, process for preparation thereof and optical element made therefrom SHOWA DENKO KABUSHIKI KAISHA (JP) 1988-09-28 EP disclosed
EP-0014785-B1 COATING METHOD AND CURABLE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 1985-06-12 EP disclosed
EP-0014785-A1 Coating method and curable compositions GENERAL ELECTRIC COMPANY (US) 1980-09-03 EP disclosed
US-4139385-A POLYTHIOETHERS, QUICK CURING GENERAL ELECTRIC COMPANY (US) 1979-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12534563-B2 Block copolymer, resin composition, stretch conductor, electronic device, and pressure-sensitive adhesive film EPB41, ITGB4, ITGB5 ALDH1A1 2727/4885TP53 4522/4885CYP3A4 2722/4885
US-20250197555-A1 ISOCYANATE COMPOSITION, MODIFIED ISOCYANATE, POLYURETHANE RESIN AND OPTICAL MATERIAL PUF60, XRCC6, XRCC5 ALDH1A1 3250/4885TP53 2428/4885CYP3A4 1326/4885
US-12297301-B2 High-molecular-weight compound and method for producing same, composition and method for producing same, resin composition, additive for lubricating oil, and lubricating oil TMT1A, TST, NOTUM ALDH1A1 2047/4885TP53 3454/4885CYP3A4 3167/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.