Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | ENPP3 | O14638 | 4/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | EEF2K | O00418 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5391329 | 0.85 | GAA (0.43) | L3MBTL1ENPP3ENPP1ALDH1A1TSHR | |
| SCHEMBL5383925 | 0.81 | KMT2A (0.42) | HSD11B1ALDH1A1KEAP1NFE2L2 | |
| SCHEMBL36384 | 0.81 | GAA (0.34) | — | |
| SCHEMBL7158788 | 0.74 | SCN8A (0.34) | PTGS2L3MBTL1PTGS1ENPP3ENPP1 | |
| SCHEMBL7047138 | 0.72 | PTGS2 (0.39) | PTGS2L3MBTL1AR | |
| SCHEMBL27621077 | 0.69 | ENPP3 (0.54) | PTGS2L3MBTL1KIF11ENPP3ENPP1 | |
| SCHEMBL28648632 | 0.69 | KMT2A (0.57) | PTGS2L3MBTL1HSD11B1ARKEAP1 | |
| SCHEMBL503702 | 0.68 | HSD11B1 (0.45) | PTGS2L3MBTL1KIF11ENPP3ENPP1 | |
| SCHEMBL3132687 | 0.68 | HSD11B1 (0.45) | PTGS2L3MBTL1KIF11ENPP3ENPP1 | |
| SCHEMBL3139775 | 0.68 | HSD11B1 (0.45) | PTGS2L3MBTL1KIF11ENPP3ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7258962-B2 | Positive-tone radiation-sensitive resin composition | JSR CORPORATION (JP) | 2007-08-21 | — | — | US | disclosed |
| US-20050244747-A1 | Positive-tone radiation-sensitive resin composition | JSR CORPORATION (JP) | 2005-11-03 | — | — | US | disclosed |