Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5626080 | 1.00 | MME (0.36) | MMECA12CA14MAPTLTA4H | |
| SCHEMBL4689740 | 1.00 | MME (0.36) | MMECA12CA14MAPTLTA4H | |
| SCHEMBL3543225 | 0.92 | KMT2A (0.33) | MMECA12CA14MEN1GAA | |
| SCHEMBL5098960 | 0.92 | KMT2A (0.33) | MMECA12CA14MEN1GAA | |
| SCHEMBL15461486 | 0.87 | MAPT (0.34) | CA12CA14MAPTGAAALDH1A1 | |
| SCHEMBL10794048 | 0.86 | CA14 (0.43) | CA12CA14MAPTALDH1A1L3MBTL1 | |
| SCHEMBL6294189 | 0.86 | CA14 (0.43) | CA12CA14MAPTALDH1A1L3MBTL1 | |
| SCHEMBL15461474 | 0.85 | NPSR1 (0.32) | MAPTALDH1A1L3MBTL1 | |
| SCHEMBL7280370 | 0.82 | LMNA (0.31) | GAA | |
| SCHEMBL6633961 | 0.80 | CTSK (0.31) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7265220-B2 | Amino acid derivatives, method for production thereof and pharmaceutical compositions comprising said derivative | LES LABORATORIES SERVIER (FR) | 2007-09-04 | — | — | US | disclosed |
| US-7049330-B2 | Cycloalkyl-substituted aryl-piperazines, piperidines and tetrahydropyridines as serotonergic agents | WYETH (US) | 2006-05-23 | — | — | US | disclosed |
| US-20050085517-A1 | Novel amino acid derivatives, method for production thereof and pharmaceutical compositions comprising said derivative | LES LABORATOIRES SERVIER (FR) | 2005-04-21 | — | — | US | disclosed |
| EP-1476421-A2 | NOVEL AMINO ACID DERIVATIVES, METHOD FOR PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAID DERIVATIVE | LES LABORATOIRES SERVIER (FR) | 2004-11-17 | — | — | EP | disclosed |
| WO-2003070690-A2 | NOVEL AMINO ACID DERIVATIVES, METHOD FOR PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAID DERIVATIVE | LES LABORATOIRES SERVIER (FR) | 2003-08-28 | — | — | WO | disclosed |
| US-20030139449-A1 | Cycloalkyl-substituted aryl-piperazines, piperidines and tetrahydropyridines as serotonergic agents | WYETH (US) | 2003-07-24 | — | — | US | disclosed |
| US-6518272-B2 | HT3 receptor agonists and antagonists; treatment of anxiety, depression, cognitive deficits, and prostate cancer | WYETH | 2003-02-11 | — | — | US | disclosed |
| US-20020156075-A1 | Cycloalkyl-substituted aryl-piperazines, piperidines and tetrahydropyridines as serotonergic agents | WYETH (FORMERLY AMERICAN HOME PRODUCTS CORPORATION) (US) | 2002-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139449-A1 | Cycloalkyl-substituted aryl-piperazines, piperidines and tetrahydropyridines as serotonergic agents | HTR5A, MC5R, CHRNA5 | MME 2822/4885CA12 4326/4885CA14 3987/4885 |
| US-20020156075-A1 | Cycloalkyl-substituted aryl-piperazines, piperidines and tetrahydropyridines as serotonergic agents | HTR5A, MC5R, CHRNA5 | MME 2822/4885CA12 4326/4885CA14 3987/4885 |
| US-20050085517-A1 | Novel amino acid derivatives, method for production thereof and pharmaceutical compositions comprising said derivative | ARGLU1, PNISR, ATIC | MME 2221/4885CA12 2322/4885CA14 2949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.