Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | PPARA | Q07869 | 3/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | AGXT | P21549 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7049659 | 0.84 | SLC6A4 (0.53) | SLC6A4SLC6A2SLC6A3KCNH2SLC7A5 | |
| SCHEMBL5308268 | 0.82 | PPARG (0.43) | PPARGPPARAPTPN7RAB9ASLC6A4 | |
| SCHEMBL5533205 | 0.81 | SLC6A9 (0.46) | SLC6A4SLC6A2SLC6A3KCNH2SLC7A5 | |
| Iodide SCHEMBL5304189 | 0.81 | PPARG (0.42) | PPARGPPARAPTPN7RAB9ASLC6A4 | |
| SCHEMBL9614092 | 0.81 | PPARG (0.53) | PPARGPPARAPTPN7RAB9ASLC6A4 | |
| SCHEMBL5530174 | 0.81 | SLC6A4 (0.43) | SLC6A4SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL5869228 | 0.81 | HTR2C (0.42) | HTR2CPPARASLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL5869687 | 0.81 | HTR2C (0.42) | HTR2CPPARASLC6A4SLC6A2 | |
| SCHEMBL7053972 | 0.80 | SLC6A4 (0.49) | SLC6A4SLC7A5 | |
| SCHEMBL145925 | 0.80 | PPARG (0.41) | PPARGPPARAPTPN7RAB9ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217696-B2 | Glycuronamides, glycosides and orthoester glycosides of fluoxetine, analogs and uses thereof | A & D BIOSCIENCE, INC. (US) | 2007-05-15 | — | — | US | disclosed |
| CN-1649600-A | Glycuronamides, glycosides and orthoester glycosides of fluoxetine and analogs and uses thereof | A AND D BIOSCIENCE INC (US) | 2005-08-03 | — | — | CN | disclosed |
| US-20050130908-A1 | Glycuronamides, glycosides and orthoester glycosides of fluoxetine, analogs and uses thereof | HOLICK MICHAEL F (US) | 2005-06-16 | — | — | US | disclosed |
| EP-1487460-A2 | GLYCURONAMIDES, GLYCOSIDES AND ORTHOESTER GLYCOSIDES OF FLUOXETINE, ANALOGS AND USES THEREOF | A & D Bioscience, Inc. (US) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003073988-A2 | GLYCURONAMIDES, GLYCOSIDES AND ORTHOESTER GLYCOSIDES OF FLUOXETINE, ANALOGS AND USES THEREOF | A & D BIOSCIENCE, INC. (US) | 2003-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050130908-A1 | Glycuronamides, glycosides and orthoester glycosides of fluoxetine, analogs and uses thereof | PYGB, GBA3, GAA | HTR2A 181/4885HTR2C 304/4885HTR2B 115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.