Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 3/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 5/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7049659 | 0.90 | SLC6A4 (0.53) | SLC7A5SLC6A4SLC6A2SLC6A3KCNK2 | |
| SCHEMBL5530174 | 0.83 | SLC6A4 (0.43) | SLC6A4SLC6A2SLC6A3NPSR1 | |
| Oxalic Acid SCHEMBL7315983 | 0.83 | SLC6A4 (0.46) | SLC6A9SLC7A5SLC6A4MEN1KMT2A | |
| SCHEMBL13050367 | 0.82 | SLC6A4 (0.66) | SLC6A9SLC7A5SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL4734874 | 0.82 | SLC6A4 (0.66) | SLC6A9SLC7A5SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL13050366 | 0.82 | SLC6A4 (0.66) | SLC6A9SLC7A5SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL5394251 | 0.81 | HTR2A (0.45) | SLC7A5SLC6A4SLC6A2SLC6A3KCNH2 | |
| Hydrochloric Acid SCHEMBL4777538 | 0.81 | SLC6A4 (0.64) | SLC6A9SLC7A5SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL7053972 | 0.80 | SLC6A4 (0.49) | SLC6A9SLC7A5SLC6A4HTR1A | |
| SCHEMBL7310728 | 0.80 | SLC6A9 (0.49) | SLC6A9SLC6A4HTR1ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761478-A2 | AN ISOLATED ATOMOXETINE IMPURITY, PROCESSES FOR THE PREPARATION OF ATOMOXETINE IMPURITIES AND THEIR USE AS REFERENCE STANDARDS | Teva Pharmaceutical Fine Chemicals S.R.L. (IT) | 2007-03-14 | — | — | EP | disclosed |
| WO-2006004979-A2 | AN ISOLATED ATOMOXETINE IMPURITY, PROCESSES FOR THE PREPARATION OF ATOMOXETINE IMPURITIES AND THEIR USE AS REFERENCE STANDARDS | TEVA PHARMACEUTICAL FINE CHEMICALS S.R.L. (IT) | 2006-01-12 | — | — | WO | disclosed |