Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7049659 | 0.86 | SLC6A4 (0.53) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL5533205 | 0.83 | SLC6A9 (0.46) | SLC6A4NPSR1SLC6A2SLC6A3 | |
| Oxalic Acid SCHEMBL7315983 | 0.82 | SLC6A4 (0.46) | SLC6A4 | |
| SCHEMBL14528299 | 0.81 | SLC6A4 (0.54) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL5394251 | 0.81 | HTR2A (0.45) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL7053972 | 0.79 | SLC6A4 (0.49) | SLC6A4ALDH1A1DRD2DRD4LMNA | |
| SCHEMBL14188840 | 0.79 | ENPP3 (0.54) | SLC6A4ACHEENPP3SLC6A2 | |
| Maleic Acid SCHEMBL11238099 | 0.78 | LMNA (0.45) | L3MBTL1LMNA | |
| SCHEMBL17280830 | 0.77 | SLC7A5 (0.59) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL7053968 | 0.76 | NOS2 (0.44) | SLC6A4OPRM1L3MBTL1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761478-A2 | AN ISOLATED ATOMOXETINE IMPURITY, PROCESSES FOR THE PREPARATION OF ATOMOXETINE IMPURITIES AND THEIR USE AS REFERENCE STANDARDS | Teva Pharmaceutical Fine Chemicals S.R.L. (IT) | 2007-03-14 | — | — | EP | disclosed |
| WO-2006004979-A2 | AN ISOLATED ATOMOXETINE IMPURITY, PROCESSES FOR THE PREPARATION OF ATOMOXETINE IMPURITIES AND THEIR USE AS REFERENCE STANDARDS | TEVA PHARMACEUTICAL FINE CHEMICALS S.R.L. (IT) | 2006-01-12 | — | — | WO | disclosed |