Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | SCN4A | P35499 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5394251 | 0.80 | HTR2A (0.45) | SLC6A4SLC7A5 | |
| SCHEMBL5533205 | 0.80 | SLC6A9 (0.46) | SLC6A4SLC6A9HTR1ASLC7A5 | |
| SCHEMBL7049659 | 0.79 | SLC6A4 (0.53) | SLC6A4SCN4ASLC7A5 | |
| SCHEMBL5530174 | 0.79 | SLC6A4 (0.43) | SLC6A4LMNADRD2DRD4ALDH1A1 | |
| SCHEMBL7053968 | 0.76 | NOS2 (0.44) | SLC6A4SMN1; SMN2SCN4ANOS2 | |
| Oxalic Acid SCHEMBL7315983 | 0.76 | SLC6A4 (0.46) | SLC6A4SLC6A9SLC7A5 | |
| SCHEMBL5285165 | 0.74 | SLC6A2 (0.57) | SLC6A4LMNADRD3SCN4A | |
| Hydrochloric Acid SCHEMBL4730954 | 0.73 | SLC6A2 (0.58) | SLC6A4LMNADRD3SCN4A | |
| SCHEMBL13050367 | 0.72 | SLC6A4 (0.66) | SLC6A4LMNASMN1; SMN2SLC6A9DRD2 | |
| SCHEMBL4734874 | 0.72 | SLC6A4 (0.66) | SLC6A4LMNASMN1; SMN2SLC6A9DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831799-B1 | COMPOUNDS ACTIVE AT A NOVEL SITE ON RECEPTOR-OPERATED CALCIUM CHANNELS USEFUL FOR TREATMENT OF NEUROLOGICAL DISORDERS | NPS PHARMA INC (US) | 2003-05-02 | — | — | EP | claimed |
| EP-0831799-B1 | COMPOUNDS ACTIVE AT A NOVEL SITE ON RECEPTOR-OPERATED CALCIUM CHANNELS USEFUL FOR TREATMENT OF NEUROLOGICAL DISORDERS | NPS PHARMA INC (US) | 2003-05-02 | — | — | EP | disclosed |