Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.59 |
| ▸ | IAPP | P10997 | 3/20 | 0.54 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.50 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CCR5 | P51681 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3274537 | 0.92 | APP (0.68) | APPIAPPKDM4EALDH1A1MAPT | |
| SCHEMBL5348242 | 0.86 | CYP1A2 (0.57) | KDM4EALDH1A1MAPTLMNAPTPN1 | |
| SCHEMBL3685390 | 0.83 | CCNC (0.58) | APPALDH1A1ALOX5OR51E2PTPN1 | |
| SCHEMBL5593842 | 0.81 | CYP1A2 (0.53) | KDM4EMAPTLMNAPTPN1 | |
| SCHEMBL5371495 | 0.81 | APP (0.49) | APPIAPPERCC1ERCC4KDM4E | |
| SCHEMBL5619763 | 0.80 | MEN1 (0.55) | APPMAPTALOX5OR51E2HIF1A | |
| SCHEMBL27972225 | 0.80 | APP (0.51) | APPIAPPKDM4EALDH1A1MAPT | |
| SCHEMBL18269500 | 0.80 | ALOX5 (0.53) | APPIAPPALDH1A1ALOX5OR51E2 | |
| SCHEMBL7737580 | 0.79 | PTPN1 (0.60) | APPALDH1A1ALOX5OR51E2GAA | |
| SCHEMBL20730239 | 0.79 | APP (0.77) | APPIAPPKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7192981-B2 | 3,4-dihydroxyhydrocinnamic acid derivative | BIONUTRIGEN CO., LTD. (KR) | 2007-03-20 | — | — | US | claimed |
| US-20060205813-A1 | Naphthalene methyl ester derivatives for treatment of diabetes; insulin receptor signalling | BIONUTRIGEN CO., LTD. (KR) | 2006-09-14 | — | — | US | claimed |
| US-7192981-B2 | 3,4-dihydroxyhydrocinnamic acid derivative | BIONUTRIGEN CO., LTD. (KR) | 2007-03-20 | — | — | US | disclosed |
| US-20060205813-A1 | Naphthalene methyl ester derivatives for treatment of diabetes; insulin receptor signalling | BIONUTRIGEN CO., LTD. (KR) | 2006-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205813-A1 | Naphthalene methyl ester derivatives for treatment of diabetes; insulin receptor signalling | GPR119, INSR, INSRR | APP 3290/4885IAPP 92/4885ERCC1 4531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.