Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.38 |
| ▸ | KCNK5 | O95279 | 1/20 | 0.38 |
| ▸ | KCNK17 | Q96T54 | 1/20 | 0.38 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5401634 | 0.91 | MAPT (0.44) | ALDH1A1SMN1; SMN2NAMPTLMNAKMT2A | |
| SCHEMBL5409102 | 0.91 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2LMNAKMT2APOLB | |
| SCHEMBL5398701 | 0.89 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2LMNAKMT2APOLB | |
| SCHEMBL5398795 | 0.89 | MAPK1 (0.49) | ALDH1A1SMN1; SMN2NAMPTLMNAKMT2A | |
| SCHEMBL5418440 | 0.89 | L3MBTL1 (0.52) | ALDH1A1KMT2AMEN1CNR2 | |
| SCHEMBL5414359 | 0.88 | KCNA5 (0.46) | ALDH1A1SMN1; SMN2LMNAKMT2AKCNA5 | |
| SCHEMBL5397914 | 0.88 | MAPK1 (0.49) | ALDH1A1SMN1; SMN2KMT2APOLBMEN1 | |
| SCHEMBL5399511 | 0.88 | KMT2A (0.48) | ALDH1A1SMN1; SMN2NAMPTLMNAKMT2A | |
| SCHEMBL5409109 | 0.87 | CHRNB2 (0.54) | ALDH1A1SMN1; SMN2KMT2APOLBMEN1 | |
| SCHEMBL5392177 | 0.87 | AURKA (0.44) | ALDH1A1SMN1; SMN2KMT2APOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7285680-B2 | β-alanine derivatives and the use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-10-23 | — | — | US | disclosed |
| US-20050256160-A1 | Beta-alanine derivatives and the use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-11-17 | — | — | US | disclosed |
| EP-1533294-A1 | BETA-ALANINE DERIVATIVE AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-05-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256160-A1 | Beta-alanine derivatives and the use thereof | TGFB1, PML, APOB | ALDH1A1 1256/4885SMN1; SMN2 57/4885NAMPT 797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.