Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 7/20 | 0.57 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.57 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5770239 | 0.88 | CTNNB1 (0.50) | OPRM1OPRD1OPRK1LMNAKMT2A | |
| SCHEMBL8331173 | 0.79 | OPRM1 (0.59) | OPRM1OPRD1OPRK1PARP1 | |
| SCHEMBL6608318 | 0.77 | OPRD1 (0.47) | OPRM1OPRD1OPRK1PARP1 | |
| Hydrochloric Acid SCHEMBL2140875 | 0.73 | OPRD1 (0.56) | OPRM1OPRD1OPRK1LMNAMAPT | |
| SCHEMBL1135994 | 0.73 | CTSD (0.49) | CTSDOPRK1LMNAALOX15HSD17B10 | |
| SCHEMBL4929198 | 0.73 | OPRD1 (1.00) | OPRM1OPRD1OPRK1 | |
| SCHEMBL5574855 | 0.71 | MAPK1 (0.45) | CTSDLMNAALOX15HSD17B10CYP3A4 | |
| SCHEMBL5766675 | 0.71 | SIRT2 (0.45) | OPRM1OPRD1OPRK1KMT2APARP1 | |
| Alcohol SCHEMBL6835135 | 0.71 | CTSD (0.62) | CTSDOPRK1LMNAALOX15HSD17B10 | |
| SCHEMBL9284587 | 0.70 | HTR7 (0.50) | LMNAMAPTHTR2BPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312336-B2 | Compounds with analgesic effect | ASTRAZENECA CANADA INC. (CA) | 2007-12-25 | — | — | US | disclosed |
| US-20040171612-A1 | Novel compounds with analgesic effect | ASTRAZENECA CANADA INC. | 2004-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171612-A1 | Novel compounds with analgesic effect | OPRL1, OPRK1, OPRM1 | OPRM1 3/4885OPRD1 4/4885CTSD 3366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.