Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 5/20 | 0.50 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 2/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5517154 | 0.75 | PARP1 (0.51) | HTR2BLMNAMAPTPARP1 | |
| SCHEMBL8828686 | 0.73 | HTR7 (0.44) | HTR7HTR3AHTR3EHTR3BADRB1 | |
| SCHEMBL11284541 | 0.72 | HTR1A (0.49) | CYP2C19HTR6MAPTPARP1 | |
| SCHEMBL16600251 | 0.72 | MAP2 (0.48) | HTR7ACVR1TGFBR1HTR3AHTR3E | |
| SCHEMBL3883327 | 0.71 | SMARCA2 (0.42) | HTR7ACVR1TGFBR1ADRB1HTR6 | |
| SCHEMBL9283309 | 0.70 | DRD2 (0.52) | HTR7HTR3AHTR3EHTR3BADRB1 | |
| SCHEMBL5193622 | 0.70 | ACVR1 (0.49) | HTR7ACVR1HTR6 | |
| SCHEMBL5399877 | 0.70 | OPRM1 (0.57) | HTR2BLMNAMAPTPARP1 | |
| SCHEMBL16466062 | 0.70 | HTR7 (0.47) | HTR7ACVR1TGFBR1HTR3AHTR3E | |
| SCHEMBL6262440 | 0.70 | RXFP1 (0.42) | HTR7ACVR1TGFBR1ADRB1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995030659-A1 | BENZIMIDAZOLE AND IMIDAZOPYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS DOPAMINERGIC AGENTS, ESP. SELECTIVE FOR THE DOPAMINE D3 RECEPTOR | WARNER-LAMBERT COMPANY (US) | 1995-11-16 | — | — | WO | disclosed |