Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5036128 | 0.93 | ALDH1A1 (0.42) | MAPTSMN1; SMN2HPGDALDH1A1RECQL | |
| SCHEMBL15880593 | 0.82 | HAO1 (0.46) | MAPTALDH1A1HAO1 | |
| SCHEMBL2468553 | 0.80 | TAS1R3 (0.45) | ALDH1A1RECQLLMNA | |
| SCHEMBL5402060 | 0.79 | ALDH1A1 (0.60) | MAPTSMN1; SMN2L3MBTL1HPGDALDH1A1 | |
| SCHEMBL2463691 | 0.78 | PPARD (0.37) | MAPTKDM4EGAA | |
| SCHEMBL589165 | 0.76 | ALDH1A1 (0.47) | SMN1; SMN2L3MBTL1HPGDALDH1A1RECQL | |
| SCHEMBL4705073 | 0.74 | ALDH1A1 (0.43) | MAPTSMN1; SMN2HPGDALDH1A1RECQL | |
| SCHEMBL16094118 | 0.74 | ABL1 (0.40) | MAPTSMN1; SMN2HPGDALDH1A1RECQL | |
| SCHEMBL4519743 | 0.73 | PKM (0.35) | MAPTL3MBTL1ALDH1A1RECQLKDM4E | |
| SCHEMBL4063606 | 0.72 | MEN1 (0.44) | ALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511473-B1 | BIS-AROMATIC ALKANOLS | NOVARTIS AG (CH) | 2013-04-17 | — | — | EP | disclosed |
| US-7169817-B2 | Bis-aromatic alkanols | IRM LLC (BM) | 2007-01-30 | — | — | US | disclosed |
| EP-1511473-A2 | BIS-AROMATIC ALKANOLS | Novartis AG (CH) | 2005-03-09 | — | — | EP | disclosed |
| US-20040048857-A1 | Treatment and/or prevention of diseases or disorders mediated by lymphocyte interactions. | IRM LLC (BM) | 2004-03-11 | — | — | US | disclosed |
| WO-2003099192-A2 | BIS-AROMATIC ALKANOLS | NOVARTIS AG (CH) | 2003-12-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040048857-A1 | Treatment and/or prevention of diseases or disorders mediated by lymphocyte interactions. | CD4, HLA-DRB1, MALT1 | MAPT 2520/4885SMN1; SMN2 1231/4885L3MBTL1 391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.