Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 5/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | PRCP | P42785 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5391659 | 1.00 | IDH1 (0.34) | IDH1GRIN2DGRIN3BCYP2B6SLC6A2 | |
| SCHEMBL5396442 | 0.84 | IDH1 (0.37) | IDH1HSD11B1CYP3A4CYP2C9ALOX15 | |
| SCHEMBL5402085 | 0.81 | IDH1 (0.35) | IDH1HSD11B1OPRM1OPRD1 | |
| SCHEMBL7070371 | 0.80 | IDH1 (0.34) | IDH1HSD11B1 | |
| SCHEMBL5385910 | 0.80 | IDH1 (0.34) | IDH1HSD11B1 | |
| SCHEMBL5389794 | 0.78 | IDH1 (0.33) | IDH1HSD11B1 | |
| SCHEMBL13562982 | 0.78 | LTB4R (0.32) | LTB4RLTB4R2 | |
| SCHEMBL5396081 | 0.77 | MITF (0.34) | IDH1HSD11B1OPRM1OPRD1 | |
| SCHEMBL682099 | 0.76 | CYP2D6 (0.36) | KCNH2CYP3A4CYP2C9CYP2C19LTB4R | |
| SCHEMBL5394706 | 0.76 | IDH1 (0.35) | IDH1SLC6A2SLC6A4SLC6A3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7297819-B2 | Open-chain alkoxyamines and their corresponding nitroxides for controlled low temperature radical polymerization | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-11-20 | — | — | US | disclosed |
| US-7297819-B2 | Open-chain alkoxyamines and their corresponding nitroxides for controlled low temperature radical polymerization | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-11-20 | — | — | US | disclosed |
| US-7297819-B2 | Open-chain alkoxyamines and their corresponding nitroxides for controlled low temperature radical polymerization | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-11-20 | — | — | US | disclosed |
| EP-1481012-B1 | OPEN-CHAIN ALKOXYAMINES AND THEIR CORRESPONDING NITROXIDES FOR CONTROLLED LOW TEMPERATURE RADICAL POLYMERIZATION | CIBA SC HOLDING AG (CH) | 2006-05-17 | — | — | EP | disclosed |
| US-20050124814-A1 | Open-chain alkoxyamines and their corresponding nitroxides for controlled low temperature radical polymerization | CIBA SPECIALTY CHEMICALS CORPORATION | 2005-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124814-A1 | Open-chain alkoxyamines and their corresponding nitroxides for controlled low temperature radical polymerization | ALOX5, NOS2, NOS1 | IDH1 1029/4885GRIN2D 2182/4885GRIN3B 3791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.