Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 9/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5394706 | 0.92 | IDH1 (0.35) | IDH1SMN1; SMN2HSD11B1OPRM1OPRD1 | |
| SCHEMBL5396442 | 0.85 | IDH1 (0.37) | IDH1HSD11B1 | |
| SCHEMBL5396081 | 0.83 | MITF (0.34) | IDH1ATMHSD11B1OPRM1OPRD1 | |
| SCHEMBL5391659 | 0.81 | IDH1 (0.34) | IDH1HSD11B1OPRM1OPRD1 | |
| SCHEMBL7070371 | 0.81 | IDH1 (0.34) | IDH1HSD11B1 | |
| SCHEMBL5385910 | 0.81 | IDH1 (0.34) | IDH1HSD11B1 | |
| SCHEMBL5402134 | 0.81 | IDH1 (0.34) | IDH1HSD11B1OPRM1OPRD1 | |
| SCHEMBL5389794 | 0.79 | IDH1 (0.33) | IDH1HSD11B1 | |
| SCHEMBL5401519 | 0.76 | OPRM1 (0.35) | IDH1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL11949109 | 0.73 | ATM (0.35) | ATMOPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7297819-B2 | Open-chain alkoxyamines and their corresponding nitroxides for controlled low temperature radical polymerization | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-11-20 | — | — | US | disclosed |
| US-7297819-B2 | Open-chain alkoxyamines and their corresponding nitroxides for controlled low temperature radical polymerization | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-11-20 | — | — | US | disclosed |
| US-7297819-B2 | Open-chain alkoxyamines and their corresponding nitroxides for controlled low temperature radical polymerization | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-11-20 | — | — | US | disclosed |
| EP-1481012-B1 | OPEN-CHAIN ALKOXYAMINES AND THEIR CORRESPONDING NITROXIDES FOR CONTROLLED LOW TEMPERATURE RADICAL POLYMERIZATION | CIBA SC HOLDING AG (CH) | 2006-05-17 | — | — | EP | disclosed |
| US-20050124814-A1 | Open-chain alkoxyamines and their corresponding nitroxides for controlled low temperature radical polymerization | CIBA SPECIALTY CHEMICALS CORPORATION | 2005-06-09 | — | — | US | disclosed |
| EP-1481012-A1 | OPEN-CHAIN ALKOXYAMINES AND THEIR CORRESPONDING NITROXIDES FOR CONTROLLED LOW TEMPERATURE RADICAL POLYMERIZATION | Ciba SC Holding AG (CH) | 2004-12-01 | — | — | EP | disclosed |
| WO-2003074572-A1 | OPEN-CHAIN ALKOXYAMINES AND THEIR CORRESPONDING NITROXIDES FOR CONTROLLED LOW TEMPERATURE RADICAL POLYMERIZATION | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124814-A1 | Open-chain alkoxyamines and their corresponding nitroxides for controlled low temperature radical polymerization | ALOX5, NOS2, NOS1 | IDH1 1029/4885SMN1; SMN2 1717/4885ATM 3172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.