Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | BACE1 | P56817 | 4/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4376556 | 0.83 | CHRNB2 (0.40) | L3MBTL1MEN1KMT2ACTSSATM | |
| SCHEMBL4384037 | 0.83 | CHRNB2 (0.40) | L3MBTL1MEN1KMT2ACTSSATM | |
| SCHEMBL5080915 | 0.82 | MEN1 (0.45) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL5080919 | 0.82 | MEN1 (0.45) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL31667777 | 0.81 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL4526992 | 0.81 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL25852154 | 0.78 | KMT2A (0.59) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL1799801 | 0.77 | HDAC3 (0.40) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL7320870 | 0.77 | MEN1 (0.50) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL2736195 | 0.77 | ATM (0.43) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7192983-B2 | Improving storage stability by reacting with hydrogen sulfate lithium- containing compound; aspartyl protease inhibitors | G.D. SEARLE & CO. (US) | 2007-03-20 | — | — | US | disclosed |
| US-20060074247-A1 | N-protected/N-substituted-beta-amino hydroxy sulfonates | G.D. SEARLE & CO. (US) | 2006-04-06 | — | — | US | disclosed |
| US-6586627-B1 | Blocking carbocyclic oxo, amines such as 2-(bis(phenylmethyl) amino)-3-phenylpropanal to form 2-(Bis(phenylmethyl)amino)-1-hydroxy-3-phenylpropylsulfonic Acid Salts, having storage stability; chemical intermediates for enzyme inhibitors | G. D. SEARLE & CO. | 2003-07-01 | — | — | US | disclosed |
| US-6147253-A | STABILIZED FORM OF N-PROTECTED/N-SUBSTITUTED ALPHA-AMINO ALDEHYDES | G. D. SEARLE & CO. (US) | 2000-11-14 | — | — | US | disclosed |
| EP-0861233-B1 | N-PROTECTED/N-SUBSTITUTED-BETA-AMINO HYDROXY SULFONATES | SEARLE & CO (US) | 2000-05-03 | — | — | EP | disclosed |
| US-5847201-A | N-protected/N-substituted-beta-amino hydroxy sulfonates | G.D. SEARLE & CO. (US) | 1998-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060074247-A1 | N-protected/N-substituted-beta-amino hydroxy sulfonates | AANAT, AASDHPPT, ALDH7A1 | L3MBTL1 3521/4885ALDH1A1 30/4885LMNA 442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.