SCHEMBL5405221

SCHEMBL5405221

C[Si](C)(c1ccc(-n2c3ccccc3c3ccccc32)cc1)c1ccc(-n2c3ccccc3c3ccccc32)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.59
L3MBTL1 Q9Y468 2/20 0.59
ATM Q13315 1/20 0.59
GPR3 P46089 1/20 0.41
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
POLB P06746 1/20 0.39
PTPN1 P18031 2/20 0.37
MAPK8 P45983 1/20 0.37
HDAC4 P56524 1/20 0.36
PGR P06401 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP2C19 P33261 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
MAPK1 P28482 2/20 0.35
HTT P42858 2/20 0.35
ALDH1A1 P00352 2/20 0.34
NR1H2 P55055 1/20 0.34
NR1H3 Q13133 1/20 0.34
KMT2A Q03164 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13127425 0.91 KDM4E (0.50) KDM4EL3MBTL1ATMGPR3ESR1
SCHEMBL13010232 0.88 KDM4E (0.59) KDM4EL3MBTL1ATMGPR3POLB
SCHEMBL13127427 0.87 KDM4E (0.46) KDM4EL3MBTL1ATMGPR3ESR1
SCHEMBL13127428 0.87 KDM4E (0.46) KDM4EL3MBTL1ATMPOLBHDAC4
SCHEMBL10206298 0.86 KDM4E (0.53) KDM4EL3MBTL1ATMGPR3ESR1
SCHEMBL15090302 0.85 KDM4E (0.61) KDM4EL3MBTL1ATMGPR3POLB
SCHEMBL14649405 0.84 KDM4E (0.55) KDM4EL3MBTL1ATMPOLBPTPN1
SCHEMBL12108670 0.83 L3MBTL1 (0.64) KDM4EL3MBTL1ATMGPR3POLB
SCHEMBL13127397 0.83 KDM4E (0.42) KDM4EL3MBTL1ATMGPR3ESR1
SCHEMBL13127398 0.83 KDM4E (0.42) KDM4EL3MBTL1ATMGPR3ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240023438-A1 CONDENSED CYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2024-01-18 US disclosed
US-20240023438-A1 CONDENSED CYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2024-01-18 US disclosed
US-20230363255-A1 CONDENSED CYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-09 US disclosed
US-20230363255-A1 CONDENSED CYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-09 US disclosed
US-11339143-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2022-05-24 US disclosed
US-20210408379-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2021-12-30 US disclosed
US-11201300-B2 Condensed cyclic compound and organic light-emitting device including condensed cyclic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-12-14 US disclosed
US-11124521-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-09-21 US disclosed
US-20210098713-A1 ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2021-04-01 US disclosed
US-10957863-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-03-23 US disclosed
US-20110121270-A1 ORGANIC LIGHT EMITTING DEVICE AND METHOD OF MANUFACTURING THE SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2011-05-26 US disclosed
US-7875369-B2 Electrical stability, electron mobility; lifetime, luminous efficiency SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2011-01-25 US disclosed
US-20100301741-A1 ORGANIC LIGHT EMITTING DEVICE SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2010-12-02 US disclosed
US-7585573-B2 Blue phosphorescent material; iridium and monoanionic bidentate ligand, acetylacetonate, in complex with pyridine or pyrimidine heterocyles substituted with electron donors; high color purity, dark blue light, low power consumption SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2009-09-08 US disclosed
US-20090211640-A1 Electron injecting layer including superacid salt, lithium salt or mixture thereof, photovoltaic device including the electron injecting layer, method of manufacturing the photovoltaic device, and organic light-emitting device including the electron injecting layer SAMSUNG MOBILE DISPLAY CO., LTD., A CORPORATION CHARTERED IN AND EXISTING UNDER THE LAWS OF THE REPUBLIC OF KOREA (KR) 2009-08-27 US disclosed
US-20090153035-A1 Heteroaromatic cycle-containing compound, method of preparing the same and organic light emitting device comprising the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2009-06-18 US disclosed
US-20080311427-A1 Organometallic complex, method of preparing the same and organic light emitting device comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2008-12-18 US disclosed
US-7413817-B2 4,4′-Bis(carbazol-9-yl)-biphenyl based silicone compound and organic electroluminescent device using the same SAMSUNG SDI CO., LTD. (KR) 2008-08-19 US disclosed
US-20080176105-A1 Heterocycle-containing organometallic complex and organic light emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2008-07-24 US disclosed
WO-2007119954-A1 PREPARING METHOD FOR ORGANIC THIN LAYER OF ORGANIC LIGHT EMITTING DEVICES USING ELECTROCHEMICAL DEPOSITION DONGJIN SEMICHEM CO., LTD (KR) 2007-10-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10957863-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CCNA1, CCNT1 KDM4E 3264/4885L3MBTL1 477/4885ATM 2232/4885
US-11124521-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CRY2, CCNT1 KDM4E 2960/4885L3MBTL1 958/4885ATM 1582/4885
US-20090153035-A1 Heteroaromatic cycle-containing compound, method of preparing the same and organic light emitting device comprising the same CCNE2, CCNC, CCNT1 KDM4E 2044/4885L3MBTL1 1854/4885ATM 2637/4885
US-11339143-B2 Condensed cyclic compound and organic light-emitting device including the same CCNT1, CCNA1, CRY1 KDM4E 2599/4885L3MBTL1 203/4885ATM 1470/4885
US-20080311427-A1 Organometallic complex, method of preparing the same and organic light emitting device comprising the same MT-CO1, COG6, INTS6 KDM4E 3671/4885L3MBTL1 345/4885ATM 4040/4885
US-20080176105-A1 Heterocycle-containing organometallic complex and organic light emitting device including the same TIMCC, ORC3, LAGE3 KDM4E 2680/4885L3MBTL1 151/4885ATM 3126/4885
US-11201300-B2 Condensed cyclic compound and organic light-emitting device including condensed cyclic compound CRY1, CCNL2, CCNE2 KDM4E 2977/4885L3MBTL1 1003/4885ATM 1151/4885
US-20240023438-A1 CONDENSED CYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE CRY1, CRY2, CCNE2 KDM4E 3091/4885L3MBTL1 1141/4885ATM 1867/4885
US-20230363255-A1 CONDENSED CYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE CRY1, CRY2, ORC3 KDM4E 3432/4885L3MBTL1 1355/4885ATM 2193/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.