SCHEMBL5405364

SCHEMBL5405364

[CH2]CCCCCCCN1CCN(CC)CC1

nearest known ligand 0.45

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 2/20 0.45
GNAO1 P09471 2/20 0.45
GNAI1 P63096 2/20 0.45
HRH3 Q9Y5N1 1/20 0.42
PAOX Q6QHF9 1/20 0.38
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
KDM1A O60341 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5394116 1.00 GNAI3 (0.45) GNAI3GNAO1GNAI1HRH3PAOX
SCHEMBL5384618 1.00 GNAI3 (0.45) GNAI3GNAO1GNAI1HRH3PAOX
SCHEMBL5390210 1.00 GNAI3 (0.45) GNAI3GNAO1GNAI1HRH3PAOX
SCHEMBL5391893 0.98 GNAI3 (0.42) GNAI3GNAO1GNAI1HRH3KDM4E
SCHEMBL1582630 0.91 KDM1A (0.40) GNAI3GNAO1GNAI1KDM4EALDH1A1
SCHEMBL508711 0.88 HRH3 (0.52) GNAI3GNAO1GNAI1HRH3PAOX
SCHEMBL508910 0.88
SCHEMBL6659172 0.88 GNAI3 (0.54) GNAI3GNAO1GNAI1HRH3PAOX
SCHEMBL6202838 0.86 GNAO1 (0.61) GNAI3GNAO1GNAI1KDM4E
SCHEMBL6663102 0.85 GNAI3 (0.50) GNAI3GNAO1GNAI1HRH3KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8461375-B2 Method for the continuous production of alkyl(meth)acrylates with multiple catalyst recycling EVONIK RÖHM GMBH (DE) 2013-06-11 US disclosed
EP-1583733-B1 IMPROVED METHOD FOR THE CONTINUOUS PRODUCTION OF ALKYL(METH)ACRYLATES WITH MULTIPLE CATALYST RECYCLING EVONIK ROEHM GMBH (DE) 2013-04-24 EP disclosed
EP-1399409-B1 METHOD FOR PRODUCING (METH)ACRYLIC ACID ESTERS BASF SE (DE) 2012-10-31 EP disclosed
US-7268251-B2 Method for producing (meth) acrylic acid esters BASF AKTIENGESELLSCHAFT (DE) 2007-09-11 US disclosed
US-20060211880-A1 Method for the continuous production of alkyl(meth)acrylates with multiple catalyst recycling ROEHM GMBH & CO. KG (DE) 2006-09-21 US disclosed
US-7026503-B2 Method for producing (meth)acrylic acid esters BASF AKTIENGESELLSCHAFT (DE) 2006-04-11 US disclosed
EP-1399408-B1 METHOD FOR PRODUCING (METH)ACRYLIC ACID ESTERS BASF AG (DE) 2006-03-22 EP disclosed
EP-1583733-A1 IMPROVED METHOD FOR THE CONTINUOUS PRODUCTION OF ALKYL(METH)ACRYLATES WITH MULTIPLE CATALYST RECYCLING Röhm GmbH & Co. KG (DE) 2005-10-12 EP disclosed
US-20040171868-A1 Method for producing (meth) acrylic acid esters BASF AKTIENGESELLSCHAFT (DE) 2004-09-02 US disclosed
CN-1525953-A Method for producing (meth) acrylic acid esters �����ɷ� 2004-09-01 CN disclosed
US-20040158096-A1 Method for producing (meth)acrylic acid esters BASF AKTIENGESELLSCHAFT (DE) 2004-08-12 US disclosed
WO-2004063140-A1 IMPROVED METHOD FOR THE CONTINUOUS PRODUCTION OF ALKYL(METH)ACRYLATES WITH MULTIPLE CATALYST RECYCLING Röhm GmbH & Co. KG (DE) 2004-07-29 WO disclosed
EP-1399408-A1 METHOD FOR PRODUCING (METH)ACRYLIC ACID ESTERS BASF AKTIENGESELLSCHAFT (DE) 2004-03-24 EP disclosed
WO-2002100814-A1 METHOD FOR PRODUCING (METH)ACRYLIC ACID ESTERS BASF AKTIENGESELLSCHAFT (DE) 2002-12-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171868-A1 Method for producing (meth) acrylic acid esters ADH1A, ADH5, ADH1C GNAI3 2674/4885GNAO1 2319/4885GNAI1 2500/4885
US-20060211880-A1 Method for the continuous production of alkyl(meth)acrylates with multiple catalyst recycling ADH5, ADH1A, ADH1C GNAI3 3050/4885GNAO1 3278/4885GNAI1 3557/4885
US-20040158096-A1 Method for producing (meth)acrylic acid esters ADH1A, ADH5, ADH1C GNAI3 2792/4885GNAO1 1771/4885GNAI1 2372/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.