Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | KCNK5 | O95279 | 1/20 | 0.41 |
| ▸ | KCNK17 | Q96T54 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5392416 | 0.93 | KCNA5 (0.43) | LMNARAB9AKCNA5KCNK3KCNK5 | |
| SCHEMBL5394169 | 0.93 | RAB9A (0.45) | LMNARAB9AKCNA5LTB4RLTB4R2 | |
| SCHEMBL5416629 | 0.92 | RAB9A (0.55) | LMNARAB9AKCNA5KCNK3KCNK5 | |
| SCHEMBL5403769 | 0.91 | RAB9A (0.45) | LMNARAB9ALTB4RLTB4R2ALDH1A1 | |
| SCHEMBL5395905 | 0.91 | LMNA (0.48) | LMNARAB9AKCNA5KCNK3KCNK5 | |
| SCHEMBL5401008 | 0.91 | RAB9A (0.52) | RAB9ALTB4RLTB4R2ALDH1A1KDM4E | |
| SCHEMBL5402540 | 0.90 | L3MBTL1 (0.46) | LMNARAB9ALTB4RLTB4R2ALDH1A1 | |
| SCHEMBL5402234 | 0.89 | RAB9A (0.48) | RAB9AALDH1A1KDM4EKMT2AHPGD | |
| SCHEMBL5392864 | 0.89 | CHRNB2 (0.48) | LMNARAB9ALTB4RLTB4R2KMT2A | |
| SCHEMBL5394436 | 0.89 | RAB9A (0.47) | LMNARAB9AALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7285680-B2 | β-alanine derivatives and the use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-10-23 | — | — | US | disclosed |
| US-20050256160-A1 | Beta-alanine derivatives and the use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-11-17 | — | — | US | disclosed |
| EP-1533294-A1 | BETA-ALANINE DERIVATIVE AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-05-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256160-A1 | Beta-alanine derivatives and the use thereof | TGFB1, PML, APOB | LMNA 308/4885RAB9A 3132/4885KCNA5 3586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.