SCHEMBL541096

SCHEMBL541096

CCCCCCc1c(O)ccc(CC)c1CC.COc1cnnnc1-c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 9/20 0.37
PPARA Q07869 1/20 0.37
ELANE P08246 2/20 0.37
PTGS2 P35354 2/20 0.36
TACR3 P29371 1/20 0.35
GPR84 Q9NQS5 1/20 0.35
PTGS1 P23219 1/20 0.35
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
APAF1 O14727 1/20 0.35
USP2 O75604 1/20 0.35
ALDH1A1 P00352 1/20 0.35
POLB P06746 1/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
HTT P42858 1/20 0.35
BLM P54132 1/20 0.35
KMT2A Q03164 1/20 0.35
ATM Q13315 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27816109 0.92 ALOX5 (0.42) ALOX5PPARAELANEPTGS2TYR
SCHEMBL14486014 0.91 PPARA (0.42) ALOX5PPARAELANEPTGS2KDM4E
SCHEMBL28781909 0.91 PPARA (0.42) ALOX5PPARAELANEPTGS2KDM4E
SCHEMBL28296116 0.87 SOAT1 (0.40) ALOX5
SCHEMBL64304 0.87 SOAT1 (0.40) ALOX5
SCHEMBL6798290 0.86 ALOX5 (0.44) ALOX5PPARAELANEPTGS2KDM4E
SCHEMBL28983211 0.85 ALOX5 (0.39) ALOX5PPARAKDM4EMEN1APAF1
SCHEMBL28775100 0.84 TACR3 (0.37) PPARATACR3GPR84KDM4EMEN1
SCHEMBL3847181 0.83 ALOX5 (0.45) ALOX5PPARAELANEPTGS2GPR84
Guaiacol SCHEMBL29291130 0.83 SOAT1 (0.37) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109820738-B High-power oil-in-water sunscreen cosmetic 广东芭薇生物科技股份有限公司 2021-11-02 CN claimed
US-8784854-B2 Cosmetic product comprising UV-blocking cosmetic composition impregnated into expanded urethane foam AMOREPACIFIC CORPORATION (KR) 2014-07-22 US claimed
US-20140134120-A1 PHOTOPROTECTIVE COMPOSITION L'OREAL (FR) 2014-05-15 US claimed
EP-2729117-A1 PHOTOPROTECTIVE COMPOSITION L'OREAL (FR) 2014-05-14 EP claimed
US-20130045258-A1 COSMETIC PRODUCT COMPRISING UV-BLOCKING COSMETIC COMPOSITION IMPREGNATED INTO EXPANDED URETHANE FOAM AMOREPACIFIC CORPORATION (KR) 2013-02-21 US claimed
US-20130045259-A1 COSMETIC PRODUCT COMPRISING UV-BLOCKING COSMETIC COMPOSITION IMPREGNATED INTO EXPANDED URETHANE FOAM AMOREPACIFIC CORPORATION (KR) 2013-02-21 US claimed
WO-2013004777-A1 PHOTOPROTECTIVE COMPOSITION L'OREAL (FR) 2013-01-10 WO claimed
US-20110014254-A1 UV-BLOCKING COSMETICS PREPARED BY BEING IMPREGNATED WITH URETHANE FOAM AMOREPACIFIC CORPORATION (KR) 2011-01-20 US claimed
WO-2004038084-A2 FABRIC CARE COMPOSITIONS THE CLOROX COMPANY (US) 2004-05-06 WO claimed
US-20040063597-A1 Fabric care compositions CLOROX COMPANY, THE 2004-04-01 US claimed
CN-118304205-A Oil-in-water triazine compound emulsion and preparation method and application thereof 广东工业大学 2024-07-09 CN disclosed
EP-2793815-B1 USE OF DERMATOLOGICAL PREPARATION COMPRISING A COMBINATION OF ACTIVE INGREDIENTS OF ONE OR MORE ALKYL ETHERS OF GLYCEROL AND ONE OR MORE PHYSIOLOGICALLY SAFE HYDROXAMIC ACIDS INOLEX GMBH (DE) 2023-10-11 EP disclosed
CN-116617116-A Combination of polyion complex particles and non-polymeric acids having two or more acid dissociation constants 莱雅公司 2023-08-22 CN disclosed
CN-113244116-B Structured composition and use thereof 广州立白企业集团有限公司 2023-04-28 CN disclosed
CN-115887245-A Calcium alginate coated tea polyphenol modified nano particle, sunscreen composition and preparation method thereof 广州玮弘祺生物科技有限公司 2023-04-04 CN disclosed
US-20100008875-A1 Composition For Skin Or Hair SHISEIDO COMPANY LTD. (JP) 2010-01-14 US disclosed
EP-2127634-A1 COMPOSITION FOR SKIN OR HAIR Shiseido Company, Limited (JP) 2009-12-02 EP disclosed
US-20050191266-A1 Cosmetic preparations containing licochalcone A and an organic thickener BEIERSDORF AG, (DE) 2005-09-01 US disclosed
WO-2004038084-A2 FABRIC CARE COMPOSITIONS THE CLOROX COMPANY (US) 2004-05-06 WO disclosed
US-20040063597-A1 Fabric care compositions CLOROX COMPANY, THE 2004-04-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140134120-A1 PHOTOPROTECTIVE COMPOSITION BROX, PLIN5, COX5A ALOX5 393/4885PPARA 2897/4885ELANE 2895/4885
US-20050191266-A1 Cosmetic preparations containing licochalcone A and an organic thickener CUTA, CYP51A1, HMGCR ALOX5 812/4885PPARA 1296/4885ELANE 1104/4885
US-20100008875-A1 Composition For Skin Or Hair CUTA, ACMSD, CYP8B1 ALOX5 1443/4885PPARA 1958/4885ELANE 3284/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.