SCHEMBL5416591

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9520169	0.80	RXRA (0.56)	PTGS2ALOX5RXRARXRBRXRG
	SCHEMBL5387633	0.79	PTGS2 (0.69)	PTGS2ALOX5RXRARXRBRXRG
	SCHEMBL6309492	0.75	PTGS2 (0.66)	PTGS2ALOX5RXRARXRBRXRG
	SCHEMBL9520300	0.75	ALOX5 (0.79)	PTGS2ALOX5RXRARXRBRXRG
	Tepoxalin SCHEMBL75441	0.75	PTGS2 (1.00)	PTGS2ALOX5RXRARXRBRXRG
	Tepoxalin SCHEMBL9519652	0.74	PTGS2 (0.98)	PTGS2ALOX5RXRARXRBRXRG
	SCHEMBL6310403	0.73	PTGS2 (0.74)	PTGS2ALOX5
	SCHEMBL9519402	0.73	PTGS2 (0.71)	PTGS2ALOX5RXRARXRBRXRG
	SCHEMBL9080028	0.72	PTGS2 (0.81)	PTGS2ALOX5RXRARXRBRXRG
	SCHEMBL9522439	0.71	PTGS2 (0.79)	PTGS2ALOX5RXRARXRBRXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.