Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL491753 | 0.79 | MTNR1A (0.46) | HPGDCYP2D6SRC | |
| SCHEMBL26914641 | 0.76 | RIPK1 (0.46) | LMNAHPGDSMN1; SMN2MAPK1 | |
| SCHEMBL11273044 | 0.75 | HPGD (0.41) | LMNAHPGDMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL6472938 | 0.75 | CYP2C19 (0.51) | LMNAMAPTSMN1; SMN2NPSR1CYP2D6 | |
| SCHEMBL10897198 | 0.75 | RIPK1 (0.46) | HPGDALOX5ALDH1A1 | |
| SCHEMBL4624319 | 0.73 | HRH1 (0.47) | — | |
| SCHEMBL2784537 | 0.72 | GABBR2 (0.48) | CHRNB2CHRNB4CHRNA3CHRNA4LMNA | |
| SCHEMBL11902127 | 0.71 | RIPK1 (0.44) | LMNAHPGDSMN1; SMN2MAPK1 | |
| SCHEMBL2843955 | 0.70 | SLC6A4 (0.50) | CACNA1C | |
| SCHEMBL8300736 | 0.70 | HTR2A (0.36) | CHRNB2CHRNB4CHRNA3CHRNA4CACNA2D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160634-B2 | Vinyl polymer and organic electroluminescent device | Shirota, Yasuhiko (JP) | 2007-01-09 | — | — | US | disclosed |
| US-20060049750-A1 | Vinyl polymer and organic electroluminescent device | SHIROTA YASUHIKO | 2006-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060049750-A1 | Vinyl polymer and organic electroluminescent device | HVCN1, VCL, ELAVL1 | CHRNB2 2434/4885CHRNB4 2643/4885CHRNA3 2045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.