SCHEMBL5420876

SCHEMBL5420876

CC(=O)CCc1ccccc1OC(C)=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.54
LMNA P02545 2/20 0.54
IAPP P10997 1/20 0.50
PTGS2 P35354 7/20 0.49
KDM4E B2RXH2 2/20 0.49
HSD17B10 Q99714 2/20 0.49
ESR1 P03372 1/20 0.49
ITGB3 P05106 1/20 0.49
ITGA2B P08514 1/20 0.49
HMGB1 P09429 1/20 0.49
HPGD P15428 1/20 0.49
TSHR P16473 1/20 0.49
GGT1 P19440 1/20 0.49
PTGS1 P23219 1/20 0.49
BLM P54132 1/20 0.49
NAPRT Q6XQN6 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
NPSR1 Q6W5P4 1/20 0.47
PPARG P37231 1/20 0.46
PPARA Q07869 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11589528 0.89 PTGS2 (0.55) ALDH1A1LMNAPTGS2KDM4EHSD17B10
SCHEMBL31112844 0.88 NPSR1 (0.59) ALDH1A1LMNAPTGS2KDM4EHSD17B10
SCHEMBL9418061 0.88 NPSR1 (0.59) ALDH1A1LMNAPTGS2KDM4EHSD17B10
SCHEMBL31112175 0.86 PTGS2 (0.46) ALDH1A1LMNAPTGS2KDM4EHSD17B10
SCHEMBL15412576 0.86 PTGS2 (0.46) ALDH1A1LMNAPTGS2KDM4EHSD17B10
SCHEMBL16065424 0.85 PPARG (0.59) ALDH1A1LMNAPTGS2KDM4EHSD17B10
SCHEMBL4032384 0.84 PTGS2 (0.54) ALDH1A1PTGS2KDM4EHSD17B10ESR1
SCHEMBL8467353 0.84 PTGS2 (0.54) ALDH1A1LMNAPTGS2KDM4EHSD17B10
SCHEMBL266525 0.84 MTNR1A (0.63) ALDH1A1LMNAIAPPMTNR1AMTNR1B
SCHEMBL30365164 0.84 MTNR1A (0.63) ALDH1A1LMNAIAPPMTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070148202-A1 Food bait comprising a specific attractant for combating tephritidae insects VALENCIA, UNIVERSIDAD POLITECNICA DE (ES) 2007-06-28 US claimed
EP-1736050-A1 FOOD BAIT COMPRISING A SPECIFIC ATTRACTANT FOR COMBATING TEPHRITID INSECTS Ecología y Protección Agrícola S.L. (ES) 2006-12-27 EP claimed
US-20240196885-A1 INSECT PEST BAIT COMPOSITION WITH ISOCYCLOSERAM AND METHOD FOR CONTROLLING INSECT PESTS SYNGENTA CROP PROTECTION AG (CH) 2024-06-20 US disclosed
CN-118206514-A Reaction method for preparing olefin by deacylation of visible light induced ketone 国科大杭州高等研究院 2024-06-18 CN disclosed
EP-4312555-A1 INSECT PEST BAIT COMPOSITION WITH ISOCYCLOSERAM AND METHOD FOR CONTROLLING INSECT PESTS Syngenta Crop Protection AG (CH) 2024-02-07 EP disclosed
CN-117222315-A Insect pest bait composition containing isoxazole insect amide and method for controlling insect pests 先正达农作物保护股份公司 2023-12-12 CN disclosed
US-20070148202-A1 Food bait comprising a specific attractant for combating tephritidae insects VALENCIA, UNIVERSIDAD POLITECNICA DE (ES) 2007-06-28 US disclosed
EP-1750512-A1 METHOD OF COMBATING FRUIT FLIES BASF AKTIENGESELLSCHAFT (DE) 2007-02-14 EP disclosed
EP-1736050-A1 FOOD BAIT COMPRISING A SPECIFIC ATTRACTANT FOR COMBATING TEPHRITID INSECTS Ecología y Protección Agrícola S.L. (ES) 2006-12-27 EP disclosed
WO-2005102054-A1 METHOD OF COMBATING FRUIT FLIES BASF AKTIENGESELLSCHAFT (DE) 2005-11-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240196885-A1 INSECT PEST BAIT COMPOSITION WITH ISOCYCLOSERAM AND METHOD FOR CONTROLLING INSECT PESTS IP6K1, IP6K2, IP6K3 ALDH1A1 4506/4885LMNA 4246/4885IAPP 1253/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.