Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 13/20 | 0.67 |
| ▸ | ANPEP | P15144 | 8/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL542252 | 1.00 | MMP2 (0.67) | MMP2ANPEPATMTSHRALDH1A1 | |
| SCHEMBL993099 | 1.00 | MMP2 (0.67) | MMP2ANPEPATMTSHRALDH1A1 | |
| SCHEMBL3784082 | 0.82 | MMP2 (0.72) | MMP2ANPEPATMALDH1A1 | |
| SCHEMBL5494889 | 0.82 | MMP2 (0.67) | MMP2ANPEPATMTSHRALDH1A1 | |
| SCHEMBL10027149 | 0.82 | MMP2 (0.67) | MMP2ANPEPATMTSHRALDH1A1 | |
| SCHEMBL10027150 | 0.82 | MMP2 (0.67) | MMP2ANPEPATMTSHRALDH1A1 | |
| SCHEMBL3783080 | 0.82 | MMP2 (0.72) | MMP2ANPEPATMALDH1A1 | |
| SCHEMBL10793356 | 0.82 | MMP2 (0.72) | MMP2ANPEPATMALDH1A1 | |
| SCHEMBL3783083 | 0.82 | MMP2 (0.72) | MMP2ANPEPATMALDH1A1 | |
| SCHEMBL3789111 | 0.82 | MMP2 (0.72) | MMP2ANPEPATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8957252-B2 | Process for preparation of lacosamide and some N-benzyl-propanamide intermediate derivatives | INDOCO REMEDIES LIMITED (IN) | 2015-02-17 | — | — | US | disclosed |
| EP-2598476-B1 | PROCESS FOR PREPARATION OF LACOSAMIDE AND SOME N-BENZYL-PROPANAMIDE INTERMEDIATE DERIVATIVES | INDOCO REMEDIES LTD (IN) | 2014-07-02 | — | — | EP | disclosed |
| US-8759582-B2 | Process for the preparation of lacosamide | NATCO PHARMA LIMITED (IN) | 2014-06-24 | — | — | US | disclosed |
| US-8759582-B2 | Process for the preparation of lacosamide | NATCO PHARMA LIMITED (IN) | 2014-06-24 | — | — | US | disclosed |
| US-20130123522-A1 | PROCESS FOR PREPARATION OF LACOSAMIDE AND SOME N-BENZYL-PROPANAMIDE INTERMEDIATE DERIVATIVES | INDOCO REMEDIES LIMITED (IN) | 2013-05-16 | — | — | US | disclosed |
| US-20130035508-A1 | PROCESS FOR THE PREPARATION OF LACOSAMIDE | NATCO PHARMA LIMITED (IN) | 2013-02-07 | — | — | US | disclosed |
| US-20130035508-A1 | PROCESS FOR THE PREPARATION OF LACOSAMIDE | NATCO PHARMA LIMITED (IN) | 2013-02-07 | — | — | US | disclosed |
| EP-2415766-A1 | METHOD FOR MANUFACTURING BENZODIAZEPINE DERIVATIVE | Zeria Pharmaceutical Co., Ltd. (JP) | 2012-02-08 | — | — | EP | disclosed |
| US-20120010401-A1 | METHOD FOR MANUFACTURING 1,5-BENZODIAZEPINE DERIVATIVE | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2012-01-12 | — | — | US | disclosed |
| US-20120010401-A1 | METHOD FOR MANUFACTURING 1,5-BENZODIAZEPINE DERIVATIVE | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130035508-A1 | PROCESS FOR THE PREPARATION OF LACOSAMIDE | CA3, CACNA1A, CA2 | MMP2 161/4885ANPEP 96/4885ATM 4570/4885 |
| US-20120010401-A1 | METHOD FOR MANUFACTURING 1,5-BENZODIAZEPINE DERIVATIVE | GABRA5, CYP3A5, GABRA1 | MMP2 4450/4885ANPEP 4090/4885ATM 3600/4885 |
| US-20130123522-A1 | PROCESS FOR PREPARATION OF LACOSAMIDE AND SOME N-BENZYL-PROPANAMIDE INTERMEDIATE DERIVATIVES | LPXN, CACNA1B, PMP22 | MMP2 430/4885ANPEP 18/4885ATM 4635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.