Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
| ▸ | FABP6 | P51161 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | TERT | O14746 | 1/20 | 0.31 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5355865 | 0.70 | ALDH1A1 (0.44) | ALDH1A1NR4A2FABP6KDM4ECYP3A4 | |
| SCHEMBL5775761 | 0.69 | NPY5R (0.50) | NPY5RTDP1ALDH1A1KDM4EHTT | |
| SCHEMBL20712932 | 0.69 | NPY5R (0.39) | NPY5RTDP1ALDH1A1KDM4EHTT | |
| SCHEMBL31078313 | 0.69 | HRH4 (0.46) | TDP1ALDH1A1NR4A2CYP2A6KEAP1 | |
| SCHEMBL31078356 | 0.68 | DYRK1A (0.40) | TDP1NR4A2KDM4EHTR3EHTR3B | |
| SCHEMBL23773829 | 0.67 | KMT2A (0.42) | NPY5RTDP1SMN1; SMN2GAA | |
| SCHEMBL3125699 | 0.67 | FABP6 (0.47) | ALDH1A1FABP6KDM4ECYP3A4 | |
| SCHEMBL4008095 | 0.65 | KEAP1 (0.41) | ALDH1A1FABP6CYP2A6KEAP1KDM4E | |
| SCHEMBL22601387 | 0.64 | NPY5R (0.39) | NPY5RTDP1FABP6CYP2A6KEAP1 | |
| SCHEMBL21885846 | 0.64 | ALDH1A1 (0.50) | ALDH1A1MAP4K1HTTADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070287726-A1 | 5-Substituted 1H-Pyrrolo [3,2-B] Pyridines | ALTANA PHARMA AG (DE) | 2007-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287726-A1 | 5-Substituted 1H-Pyrrolo [3,2-B] Pyridines | GIPR, VIP, PGC | NPY5R 26/4885TDP1 4580/4885ALDH1A1 777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.