Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4795527 | 0.96 | EIF4A1 (0.37) | KMT2AHIF1AKDM4EALDH1A1CASP1 | |
| SCHEMBL4797063 | 0.91 | KDM4E (0.37) | KMT2AHIF1AKDM4EALDH1A1HPGD | |
| SCHEMBL5422759 | 0.89 | NPSR1 (0.35) | KMT2AHIF1AKDM4EALDH1A1HPGD | |
| SCHEMBL7785450 | 0.87 | EIF4A1 (0.38) | KMT2AHIF1AKDM4EALDH1A1POLB | |
| SCHEMBL27748008 | 0.85 | HIF1A (0.35) | KMT2AHIF1AKDM4ECASP1CASP7 | |
| SCHEMBL6131930 | 0.84 | L3MBTL1 (0.39) | KMT2AKDM4EALDH1A1POLBHPGD | |
| SCHEMBL7785467 | 0.83 | KDM4E (0.39) | KMT2AKDM4EALDH1A1HPGDCASP1 | |
| SCHEMBL7784037 | 0.83 | MAPT (0.38) | KMT2AHIF1AKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL1848196 | 0.81 | PLA2G2A (0.41) | KMT2AKDM4EALDH1A1POLBHPGD | |
| SCHEMBL6131929 | 0.80 | KMT2A (0.39) | KMT2AHIF1AKDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070145337-A1 | Photochromic 2H-naphthopyrans | TRANSITIONS OPTICAL, INC. | 2007-06-28 | — | — | US | disclosed |