Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REV1 | Q9UBZ9 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | EED | O75530 | 1/20 | 0.33 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.33 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.33 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27693406 | 0.82 | REV1 (0.35) | REV1KDM4ERXFP1LMNANPC1 | |
| SCHEMBL5429190 | 0.80 | ALDH1A1 (0.46) | REV1KDM4ERXFP1LMNANPC1 | |
| SCHEMBL5732124 | 0.79 | EED (0.35) | REV1KDM4ERXFP1LMNANPC1 | |
| SCHEMBL5429747 | 0.73 | ALDH1A1 (0.35) | REV1KDM4ELMNANPC1RAB9A | |
| SCHEMBL23412814 | 0.70 | KDM4E (0.50) | REV1KDM4ERXFP1LMNANPSR1 | |
| SCHEMBL2419233 | 0.69 | RBP4 (0.41) | REV1KDM4ELMNACHRM2CHRM4 | |
| SCHEMBL2418493 | 0.69 | ALDH1A1 (0.42) | REV1KDM4ELMNANPC1RAB9A | |
| SCHEMBL750673 | 0.68 | RBP4 (0.55) | KDM4ELMNANPSR1ALDH1A1MAPT | |
| SCHEMBL17398128 | 0.68 | QDPR (0.45) | KDM4ELMNANPC1RAB9AALDH1A1 | |
| SCHEMBL3160325 | 0.67 | ALDH1A1 (0.48) | LMNANPC1NPSR1ALDH1A1PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070099929-A1 | Substituted thiophenes | AICURIS GMBH & CO. KG (DE) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099929-A1 | Substituted thiophenes | TPMT, HAVCR2, MTAP | REV1 964/4885KDM4E 2012/4885RXFP1 4860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.