SCHEMBL825817

SCHEMBL825817

Nc1cccc2nccnc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.54
ALDH1A1 P00352 6/20 0.54
KMT2A Q03164 5/20 0.54
KDM4E B2RXH2 4/20 0.54
MEN1 O00255 4/20 0.54
POLB P06746 3/20 0.54
USP2 O75604 1/20 0.54
HSD17B10 Q99714 4/20 0.48
HIF1A Q16665 2/20 0.48
NCF1 P14598 1/20 0.45
NR4A2 P43354 1/20 0.39
TDP2 O95551 2/20 0.38
APAF1 O14727 1/20 0.38
CASP3 P42574 1/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
LMNA P02545 2/20 0.38
HSP90AA1 P07900 2/20 0.38
HSP90AB1 P08238 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL544243 0.84 NCF1 (0.54) MAPTALDH1A1KMT2AKDM4EMEN1
Hydrochloric Acid SCHEMBL26697692 0.82 NCF1 (0.52) MAPTALDH1A1KMT2AKDM4EMEN1
8-Aminoquinoline SCHEMBL860459 0.81 LMNA (0.53) MAPTALDH1A1KMT2AKDM4EMEN1
Quinoxaline SCHEMBL11559513 0.77 NCF1 (0.56) MAPTALDH1A1KMT2AKDM4EMEN1
8-Aminoquinoline SCHEMBL28078884 0.76 ALDH1A1 (0.63) MAPTALDH1A1KMT2AKDM4EMEN1
SCHEMBL3069598 0.75 KDM4E (0.58) MAPTALDH1A1KMT2AKDM4EMEN1
SCHEMBL17690782 0.73 MEN1 (0.46) MAPTALDH1A1KMT2AKDM4EMEN1
SCHEMBL12747772 0.71 KDM4E (0.54) MAPTALDH1A1KMT2AKDM4EMEN1
8-Aminoquinoline SCHEMBL159694 0.71 LMNA (0.61) MAPTALDH1A1KMT2AKDM4EMEN1
SCHEMBL3253606 0.71 KDM4E (0.54) MAPTALDH1A1KMT2AKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110867603-B Polypyrrole-quinoxaline-negative-electrode-based all-water-system mixed flow battery and preparation method thereof 常州大学 2022-03-22 CN claimed
CN-110867603-A Polypyrrole-quinoxaline-negative-electrode-based all-water-system mixed flow battery and preparation method thereof 常州大学 2020-03-06 CN claimed
CN-110669058-A Tricyclic quinolone carboxylic acid and preparation method thereof 江西农业大学 2020-01-10 CN claimed
CN-107805223-A A kind of synthetic method of the sulfonic acid chloride of quinoxaline 5 广东莱佛士制药技术有限公司 2018-03-16 CN claimed
CN-103619846-A 1-aryl-4-methyl-[1,2,4]triazolo[4,3-a]quinoxaline derivatives JANSSEN PHARMACEUTICA NV 2014-03-05 CN claimed
EP-2588144-A2 DETECTING TARGETS USING MASS TAGS AND MASS SPECTROMETRY Ventana Medical Systems, Inc. (US) 2013-05-08 EP claimed
WO-2012003478-A2 DETECTING TARGETS USING MASS TAGS AND MASS SPECTROMETRY VENTANA MEDICAL SYSTEMS, INC. (US) 2012-01-05 WO claimed
CN-100503581-C Poly (5-aminoquinoxaline) and its use NISSAN CHEMICAL IND LTD (JP) 2009-06-24 CN claimed
EP-1361244-B1 Poly(5-aminoquinoxalines); preparation and use thereof NISSAN CHEMICAL IND LTD (JP) 2006-10-18 EP claimed
US-6822069-B2 CAN BE APPLIED AS AN ACTIVE SUBSTANCE OR AN ELECTRODE MATERIAL FOR A BATTERY, AN ORGANIC ELECTROLUMINESCENCE DEVICE MATERIAL, A SEMICONDUCTOR, AND A NONLINEAR-TYPE OPTICAL MATERIAL NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2004-11-23 US claimed
US-20030215701-A1 Poly (5-aminoquinoxalines) and use thereof NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2003-11-20 US claimed
CN-1456554-A Poly (5-aminoquinoxaline) and its use NISSAN CHEMICAL IND LTD (JP) 2003-11-19 CN claimed
EP-1361244-A1 Poly(5-aminoquinoxalines); preparation and use thereof NISSAN CHEMICAL INDUSTRIES LTD. (JP) 2003-11-12 EP claimed
EP-0341476-A2 4-Aza-1,10-phenanthroline derivates BAYER AG (DE) 1989-11-15 EP claimed
JP-1319483-A None JP disclosed
US-12606533-B2 3-phenylpropylamine derivative DAIICHI SANKYO COMPANY, LIMITED (JP) 2026-04-21 US disclosed
US-20250353824-A1 3-PHENYLPROPYLAMINE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2025-11-20 US disclosed
JP-H01319483-A 4-AZA-1,10-PHENANTHROLINE DERIVATIVE BAYER AG 1989-12-25 JP disclosed
EP-0341476-A2 4-Aza-1,10-phenanthroline derivates BAYER AG (DE) 1989-11-15 EP disclosed
EP-0341476-A2 4-Aza-1,10-phenanthroline derivates BAYER AG (DE) 1989-11-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250353824-A1 3-PHENYLPROPYLAMINE DERIVATIVE SF1, SF3A1, SFXN1 MAPT 2719/4885ALDH1A1 358/4885KMT2A 1381/4885
US-12606533-B2 3-phenylpropylamine derivative SF3A1, SF1, HTR1D MAPT 4210/4885ALDH1A1 357/4885KMT2A 1072/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.